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Now showing items 1773-1792 of 8066
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Differential effects of normoxic versus hypoxic derived breast cancer paracrine factors on brain endothelial cells
(MPDI, 2021)The blood-brain barrier (BBB) is a central nervous system protective barrier formed primarily of endothelial cells that regulate the entry of substances and cells from entering the brain. However, the BBB integrity is ... -
Differential sensitivity of two endothelial cell lines to hydrogen peroxide toxicity: Relevance for in vitro studies of the blood–brain barrier
(MPDI, 2020)Oxidative stress (OS) has been linked to blood–brain barrier (BBB) dysfunction which in turn has been implicated in the initiation and propagation of some neurological diseases. In this study, we profiled, for the first ... -
Differentially expressed serum proteins from obese Wistar rats as a risk factor for obesity-induced diseases
(Springer Nature, 2020)Obesity is a chronic disease that negatively affects life expectancy through its association with life-threatening diseases such as cancer and cardiovascular diseases. Expression proteomics combined with in silico interaction ... -
Differentials in the prevalence of acute respiratory infections among under-five children: An analysis of 37 sub-Saharan countries
(Sage, 2023-01-26)Objective. We investigated the prevalence and risk factors of ARI in children under 5years old in 37 SSA countries. Methods. Data from Demographic and Health Survey (DHS) of 37 African countries was examined in this ... -
Differentiation and development: The case of the Xolobeni community in the Eastern Cape, South Africa
(PLAAS, 2019-11-15)Most agrarian scholars argue that long historic processes of colonialism, capitalist development and implementation of neo-liberal structural policies in Sub-Saharan Africa have resulted in deagrarianisation and its sub-genre ... -
‘A difficult conversation’: Community stakeholders’ and key informants’ perceptions of the barriers to talking about sex and HIV with adolescents and young people in KwaZulu-Natal, South Africa
(Culture, Health & Sexuality, 2023)Adolescence and young adulthood are important periods of transition and therefore for action and intervention to ensure future sexual and reproductive health (SRH). Caregiver-adolescent communication about sex and sexuality ... -
Diffracting diffractive readings of texts as methodology: Some propositions
(Taylor & Francis, 2019-01-30)Re-turning to our experiences of putting a diffractive methodology to work ourselves, as well as engaging with the writings of Donna Haraway and Karen Barad, we produce some propositions regarding a diffractive methodology ... -
Diffracting learning/teaching entanglements: A South African vice-chancellor’s perspective
(Routledge, 2016)This chapter considers data from interviews conducted with eight vice-chancellors from both historically advantaged and disadvantaged higher education institutions (HEIs) in South Africa, as part of a larger national project ... -
Diffracting reflection: a move beyond reflective practice
(UNISA Press, 2017)Reflective practice has become a core component in higher education studies. In the health sciences, reflective tasks are required throughout the undergraduate programmes, yet many students struggle to find value in these ... -
Diffracting socially just pedagogies through stained glass
(South African Association for Research and Development in Higher Education (SAARDHE), 2016)This article emerges from our relationship with Theo Combrinck, a colleague, a passionate social and academic activist, a recovering addict and a PhD student, who left our living space during 2014 - a death that was ... -
Diffraction or reflection? Sketching the contours of two methodologies in educational research
(Taylor & Francis, 2017)Internationally, an interest is emerging in a growing body of work on what has become known as ‘diffractive methodologies’ drawing attention to ontological aspects of research. Diffractive methodologies have largely been ... -
A diffractive exploration of affect: Learning, research and teaching in obstetrics
(South African Association for Research and Development in Higher Education (SAARDHE), 2016)Instances of abuse, neglect and disrespect to women in labour are not uncommon in South Africa's public health birthing facilities. These social injustices are surrounded by a pervasive silence that confronts undergraduate ... -
A diffractive reading of dialogical feedback through the political ethics of care
(Taylor & Francis, 2016)With regard to improving higher education feedback practices, there is an increasing interest in using the efficacy of dialogue rather than the more traditional unidirectional approaches. We build on this impetus by ... -
Diffuse staining for activated NOTCH1 correlates with NOTCH1 mutation status and is associated with worse outcome in adenoid cystic carcinoma
(Lippincott, Williams & Wilkins, 2017)NOTCH1 is frequently mutated in adenoid cystic carcinoma (ACC). To test the idea that immunohistochemical (IHC) staining can identify ACCs with NOTCH1 mutations, we performed IHC for activated NOTCH1 (NICD1) in 197 cases ... -
Digital development, inequalities & the Sustainable DevelopmentGoals: What does‘Leave No-One Behind’mean for ICT4D?
(Taylor and Francis Group, 2023)The United Nations’Sustainable Development Goals (SDGs) place greatemphasis on inequalities and pledge toleave no-one behind. For thefield of digital development, this objective presents a particularchallenge. While ... -
Digital gaming for cross-cultural learning: Development of a social constructivist game- based learning model at a South African University
(IGI Global, 2023)Although game-based learning has gained significant attention in higher education globally, it is difficult to harness its engagement and interactions to improve student success. This paper argues that the use of digital ... -
Digital literacy: The quest of an inclusive definition
(AOSIS, 2018)Forces of globalisation and economic competition enhanced by, among others, the digital technologies, are radically transforming the social context. Digital technologies are characterised by a powerful and pervasive ... -
Digital media usage and prevalence of internet addiction among undergraduate students in South Africa
(The Technical University of Kenya, 2019)The use of Internet and digital media in the academic sector has significantly improved knowledge creation. The Internet has particularly proven itself to be a valuable resource in the enhancement of knowledge production ... -
‘Digital Natives’ Require Basic Digital Literacy Skills
(University of the Western Cape, 2016)This paper discusses a Digital Academic Literacy (DAL) Programme at the University of the Western Cape (UWC). It highlights the programme's response to and alignment with emerging South African Higher Education (HE) national ... -
Digital storytelling for policy impact: Perspectives from co-producing knowledge for food system governance in South Africa
(Bristol University Press, 2022)Post-positivist critics of the linear-rational understanding of the role of knowledge in decision making have long argued the need for the construction of socially robust knowledge to illuminate policy problems from a ...