Browsing by Subject "Anticancer"
Now showing items 1-5 of 5
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Green synthesis of metallic nanoparticles using some selected medicinal plants from southern africa and their biological applications
(MDPI, 2021)The application of metallic nanoparticles (MNPs), especially that of silver, gold, cobalt, and zinc as antimicrobial, anticancer, drug delivery, contrast, and bioimaging agents has transformed the field of medicine. Their ... -
An insight into the mechanism of holamine- and funtumine-induced cell death in cancer cells
(MDPI, 2020)Holamine and funtumine, steroidal alkaloids with strong and diverse pharmacological activities are commonly found in the Apocynaceae family of Holarrhena. The selective anti-proliferative and cell cycle arrest effects of ... -
New palladium (II) complexes from halogen substituted Schiff base ligands: Synthesis, spectroscopic, biological activity, density functional theory, and molecular docking investigations
(Inorganica Chimica Acta, 2023)Two novel palladium (II) complexes Pd(L1)2 and Pd(L2)2 derived from ON donor bidentate ligands: 2-(((2-bromo-4-chlorophenyl)imino)methyl)phenol (HL1) and 2-(((-bromo-4-methylphenyl)imino)methyl)phenol (HL2) are reported. ... -
Oxazinethione derivatives as a precursor to pyrazolone and pyrimidine derivatives: Synthesis, biological activities, molecular modeling, adme, and molecular dynamics studies
(MDPI, 2021)In this study, we used oxazinethione as a perfect precursor to synthesize new pyrimidine and pyrazole derivatives with potent biological activities. Biological activities were determined for all compounds against A. flavus, ... -
Synthesis, characterization, and DNA-binding kinetics of new pd(ii) and pt(ii) thiosemicarbazone complexes: Spectral, structural, and anticancer evaluation
(Hindawi, 2020)In a bid to come up with potential anticancer agents, a class of thiosemicarbazone ligands bearing substituted thiophene were synthesized followed by complexation with various Pd(II) and Pt(II) metal precursors. The ligands ...