Browsing Faculty of Natural Sciences by Title
Now showing items 476-495 of 2571
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Covid-19 among adults living with HIV: Correlates of mortality among public sector healthcare users in Western Cape, South Africa
(Wiley, 2023)Introduction: While a large proportion of people with HIV (PWH) have experienced SARS-CoV-2 infections, there is uncertainty about the role of HIV disease severity on COVID-19 outcomes, especially in lower-income settings. ... -
Covid-19 and cancer therapy: Interrelationships and management of cancer cases in the era of Covid-19
(Hindawi, 2021)'e COVID-19 global epidemic poses this generation’s biggest worldwide public health challenge probably since the 1918 influenza epidemic. Recent reports on two new variants have triggered a dramatic upsurge in research ... -
Crataegus monogyna and centella asiatica extracts as inhibitors of cathepsin s
(Horizon Research Publishing, 2022)Cathepsin cysteine proteases such as cathepsin S are responsible for the unfavorable and irreversible dysregulation of extracellular matrix (ECM) proteolysis found in cardiomyopathy, heart valve diseases and atherosclerosis. ... -
Creating opportunities through science symposia
(South African Assn. For The Advancement Of Science, 2020)For most marine scientists, unless we work in the field of fisheries development or at the interface of science and policy, it is rare to feel that we are making an impact on the lives of people in the wider community. ... -
Crispr-based multi-gene integration strategies to create saccharomyces cerevisiae strains for consolidated bioprocessing
(MDPI, 2022)Significant engineering of Saccharomyces cerevisiae is required to enable consolidated bioprocessing (CBP) of lignocellulose to ethanol. Genome modification in S. cerevisiae has been successful partly due to its efficient ... -
Criteria to facilitate the implementation of woman-centred care in childbirth units of Limpopo Province, South Africa (Part 2)
(OASIS OpenJournals, 2013)Background: Facilitation of mutual participation, respectful and egalitarian relationship between the mother and the midwife during childbirth is a critical aspect. This article delineated the criteria that would facilitate ... -
Critical appraisal of clinical guidelines for prevention and management of doxorubicin-induced cardiotoxicity
(Journal of Oncology Pharmacy Practice, 2022)Objective: Doxorubicin is a valuable chemotherapeutic drug; however, it is associated with a high risk of cardiotoxicity. Several institutions and organizations have developed guidelines for risk factor assessment, monitoring, ... -
Critical evaluation of two models of flow cytometers for the assessment of sperm DNA fragmentation: an appeal for performance verification
(Medknow Publications, 2019)Lack of standardized, reproducible protocols and reference values is among the challenges faced when using new or upgraded versions of instruments in reproductive laboratories and flow cytometry. Terminal deoxynucleotidyl ... -
A critical look at the mass-metallicity-star formation rate relation in the local universe. I. An improved analysis framework and confounding systematics
(Institute of Physics Publishing, 2014)It has been proposed that the (stellar) mass-(gas) metallicity relation of galaxies exhibits a secondary dependence on star formation rate (SFR), and that the resulting M∗-Z-SFR relation may be redshift-invariant, i.e., ... -
Cross-sectional study of prevalence and determinants of uncontrolled hypertension among South African adult residents of Mkhondo municipality
(Springer Nature, 2020)Achieving the blood pressure treatment target in individuals with hypertension is a serious global health challenge. Furthermore, the actual burden of uncontrolled hypertension is poorly understood, especially in the ... -
Cross-sectional study of the association of 5 single nucleotide polymorphisms with enalapril treatment response among South African adults with hypertension
(NLM (Medline), 2021-11-19)This study investigates the association of 5 single nucleotide polymorphisms (SNPs) in selected genes (ABO, VEGFA, BDKRB2, NOS3, and ADRB2) with blood pressure (BP) response to enalapril. The study further assessed genetic ... -
Cross-shelf movement of chrysaora fulgida (scyphozoa; discomedusae) off namibia inferred from stable isotopes (δ15n and δ13c)
(Taylor and Francis Group, 2021)Large and small specimens of two species of metagenic Scyphozoa (true jellyfishes) can be found in nearshore waters off central Namibia throughout the year. Whereas populations of Chrysaora ... -
Cross-species multiple environmental stress responses: An integrated approach to identify candidate genes for multiple stress tolerance in sorghum (Sorghum bicolor (L.) Moench) and related model species
(Public Library of Science, 2018)BACKGROUND Crop response to the changing climate and unpredictable effects of global warming with adverse conditions such as drought stress has brought concerns about food security to the fore; crop yield loss is a major ... -
Crystal engineering and thin-film deposition strategies towards improving the performance of kesterite photovoltaic cell
(Elsevier, 2021)With high absorption coefficient (104 cm 1), optimal bandgap (~1.5 eV), low toxicity and the abundance of its constituent elements, kesterite (Cu2ZnSnS4 or CZTS) displays the properties of an ideal photovoltaic material. ... -
Crystal structure of 2,2′-(propane- 1,3-dilylbis(azaneylylidene))bis(methanylylidene) bis(4-methylphenol), C19H22N2O2
(De Gruyter, 2021)C19H22N2O2, monoclinic, P21/c (no. 14), a = 19.3063(4) Å, b = 5.83200(10) Å, c = 14.7996(3) Å, β = 92.715(1)°, V = 1664.48(6) Å3, Z= 4, Rgt(F) = 0.0423, wRref (F2) = 0.1102, T = 100(2) K. -
The crystal structure of fac-tricarbonyl((pyridin-2-yl)methanamino-κ2N,N′)-((pyridin-2-yl)methanamino-κN)rhenium(I) nitrate,C15H16O3N4Re
(De gruyter, 2023)Abstract: C15H16O3N4Re, triclinic, P1̄ (no. 2), a = 7.4939(2) Å, b = 10.1316(2) Å, c = 13.8351(3) Å, α = 103.453(2)°, β = 101.992(2)°, γ = 107.880(2)°, V = 926.98(4) Å3, Z = 2, Rgt(F) = 0.0341, wRref(F2) = 0.0861, T = 150 K. -
Crystal structure of saposin B reveals a dimeric shell for lipid binding
(National Academy of Sciences, 2003)Saposin B is a small, nonenzymatic glycosphingolipid activator protein required for the breakdown of cerebroside sulfates (sulfatides) within the lysosome. The protein can extract target lipids from membranes, forming ... -
Crystal structure, Hirshfeld surface analysis and DFT studies of 5-(adamantan-1-yl)-3-[(4- chlorobenzyl)sulfanyl]-4-methyl4H-1,2,4-triazole, a potential 11βHSD1 inhibitor
(Scientific Reports, 2019)5-(Adamantan-1-yl)-3-[(4-chlorobenzyl)sulfanyl]-4-methyl-4H-1,2,4-triazole (4) was identifed as a potential 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor and this paper describes the in-depth structural ... -
Crystal structure, hirshfeld surface analysis and dft studies of 5-(adamantan-1-yl)-3-[(4-chlorobenzyl)sulfanyl]-4-methyl-4h-1,2,4-triazole, a potential 11β-hsd1 inhibitor
(Scientific Reports, 2019)5-(Adamantan-1-yl)-3-[(4-chlorobenzyl)sulfanyl]-4-methyl-4H-1,2,4-triazole (4) was identified as a potential 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor and this paper describes the in-depth structural ... -
Curdlan–chitosan electrospun fibers as potential scaffolds for bone regeneration
(MPDI, 2021)Polysaccharides have received a lot of attention in biomedical research for their high potential as scaffolds owing to their unique biological properties. Fibrillar scaffolds made of chitosan demonstrated high promise in ...