Browsing Faculty of Natural Sciences by Title
Now showing items 498-517 of 2571
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Current Status of Next-Generation Sequencing Approaches for Candidate Gene Discovery in Familial Parkinson´s Disease
(Frontiers in Genetics, 2022)Parkinson’s disease is a neurodegenerative disorder with a heterogeneous genetic etiology. The advent of next-generation sequencing (NGS) technologies has aided novel gene discovery in several complex diseases, including ... -
A cursory look at the fishmeal/oil industry from an ecosystem perspective
(Frontiers Media, 2021)By supporting the fishmeal industry, are we competing with marine predators? Should we be taking away food from marine predators to subsidize agriculture? If not for human consumption, should forage fish be left in the ... -
Cyber physical systems dependability using cps-iot monitoring
(MPDI, 2021)Recently, vast investments have been made worldwide in developing Cyber-Physical Systems (CPS) as solutions to key socio-economic challenges. The Internet-of-Things (IoT) has also enjoyed widespread adoption, mostly for ... -
Cyber security education is as essential as “the three R's”
(CELLPRESS, 2019)Smartphones have diffused rapidly across South African society and constitute the most dominant information and communication technologies in everyday use. That being so, it is important to ensure that all South Africans know ... -
Cytotoxic and cell cycle arrest properties of two steroidal alkaloids isolated from Holarrhena floribunda (G. Don) T. Durand & Schinz leaves
(BMC, 2019)The plant Holarrhena floribunda (H. floribunda; G. Don) is indigenous to sub-Saharan Africa and is traditionally used to treat several ailments. The present study was carried out to isolate and characterize bioactive ... -
Cytotoxic, cytostatic and HIV-1 PR inhibitory activities of the soft coral litophyton arboreum
(MDPI, 2013)Bioassay-guided fractionation using different chromatographic and spectroscopic techniques in the analysis of the Red Sea soft coral Litophyton arboreum led to the isolation of nine compounds; sarcophytol M (1), alismol ... -
DAMPD: a manually curated antimicrobial peptide database
(Oxford University Press, 2012)The demand for antimicrobial peptides (AMPs) is rising because of the increased occurrence of pathogens that are tolerant or resistant to conventional antibiotics. Since naturally occurring AMPs could serve as templates ... -
Dark energy homogeneity in general relativity: Are we applying it correctly?
(Springer, 2016)Thus far, there does not appear to be an agreed (or adequate) definition of homogeneous dark energy (DE). This paper seeks to define a valid, adequate homogeneity condition for DE. Firstly, it is shown that as long as ... -
Data Management Plans in the genomics research revolution of Africa: Challenges and Recommendations
(Elsevier, 2021)Drafting and writing a data management plan (DMP) is increasingly seen as a key part of the academic research process. A DMP is a document that describes how a researcher will collect, document, describe, share, and preserve ... -
Database for exploration of functional context of genes implicated in ovarian cancer
(Oxford Journals, 2009)Ovarian cancer (OC) is becoming the most common gynecological cancer in developed countries and the most lethal gynecological malignancy. It is also the fifth leading cause of all cancer-related deaths in women. The ... -
Dating detrital zircon from the gold-bearing Ventersdorp contact reef in the Ventersdorp supergroup of South Africa
(Elsevier, 2021)The Ventersdorp Contact Reef (VCR) at the base of the >4.5 km-thick volcanosedimentary Ventersdorp Supergroup unconformably overlies the Witwatersrand Supergroup and is the second youngest mineable reef in the Witwatersrand ... -
DDEC: Dragon databaseof genes implicated in esophageal cancer
(BioMed Central, 2009)Esophageal cancer ranks eighth in order of cancer occurrence. Its lethality primarily stems from inability to detect the disease during the early organ-confined stage and the lack of effective therapies for advanced-stage ... -
DDESC: Dragon database for exploration of sodium channels in human
(BMC Cancer, 2008)Sodium channels are heteromultimeric, integral membrane proteins that belong to a superfamily of ion channels. The mutations in genes encoding for sodium channel proteins have been linked with several inherited genetic ... -
DDPC: Dragon database of genes associated with prostate cancer
(Oxford Journals, 2011)Prostate cancer (PC) is one of the most commonly diagnosed cancers in men. PC is relatively difficult to diagnose due to a lack of clear early symptoms. Extensive research of PC has led to the availability of a large amount ... -
Deaf telephony: community-based co-design
(Wiley, 2011)The process of community-based co-design is one that explores various solution configurations in a multi-dimensional design space whose axes are the different dimensions of requirements and the various dimensions of designer ... -
Deaf telephony: community-based co-design (case study)
(Wiley, 2011)The process of community-based co-design is one that explores various solution configurations in a multi-dimensional design space whose axes are the different dimensions of requirements and the various dimensions of designer ... -
A decade of plant proteomics and mass spectrometry: Translation of technical advancements to food security and safety issues
(Wiley, 2013)Tremendous progress in plant proteomics driven by mass spectrometry (MS) techniques has been made since 2000 when few proteomics reports were published and plant proteomics was in its infancy. These achievements include ... -
Decoding heavy metal stress signalling in plants: Towards improved food security and safety
(MDPI, 2020)The mining of heavy metals from the environment leads to an increase in soil pollution, leading to the uptake of heavy metals into plant tissue. The build-up of toxic metals in plant cells often leads to cellular damage ... -
Decorum in nature: Impala (Aepyceros melampus melampus) dung middens follow spatial point patterns in Mukuvisi Woodland, Zimbabwe
(Taylor and Francis Group, 2023)Guided by the Optimum Foraging Theory,the Avoidance Concept, and assuming that the impala Aepyceros melampus melampus defecate purposevely at dung middens, we hypothe-sized that the impala’s dung midden locations do not: ... -
Decorum in nature: impala (Aepyceros melampus melampus) dung middens follow spatial point patterns in Mukuvisi Woodland, Zimbabwe
(Geology, Ecology, and Landscapes, 2023)Guided by the Optimum Foraging Theory,the Avoidance Concept, and assuming that the impala Aepyceros melampus melampus defecate purposevely at dung middens, we hypothesized that the impala’s dung midden locations do not: ...