Now showing items 1-14 of 14

  • Antimicrobial resistant Gram-positive cocci in pregnant mothers with aerobic vaginitis 

    Kaambo, Eveline; Abrantes, Pedro Miguel dos Santos; McArthur, Carole P.; Africa, Charlene W.J. (Infection Control Africa Network (ICAN), 2016)
    The vaginal microbiota of a healthy asymptomatic woman consists of an extensive diversity of anaerobic and aerobic bacterial genera and species dominated by the microaerophilic genus Lactobacillus , known to inhibit the ...
  • Candida antifungal drug resistance in sub-Saharan African populations: A systematic review 

    Africa, Charlene W.J.; Abrantes, Pedro Miguel dos Santos (Science Navigation Group, 2017)
    BACKGROUND: Candida infections are responsible for increased morbidity and mortality rates in at-risk patients, especially in developing countries where there is limited access to antifungal drugs and a high burden of HIV ...
  • Candida species carriage in diabetic patients in Misrata, Libya 

    Esmaio, Mustafa Hassan Mustafa; Abrantes, Pedro Miguel dos Santos; Africa, Charlene Wilma Joyce (Medpharm Publications, 2017)
    Background: There is a paucity of studies describing the prevalence and antimicrobial profiles of Candida in Libya. Limited treatment choices in the antifungal armamentarium in public healthcare settings in Africa require ...
  • Carbapenem resistance expressed by Gram-negative bacilli isolated from a cohort of Libyan patients 

    Shallouf, Mohamed; Abrantes, Pedro Miguel dos Santos; Africa, Charlene W.J. (BioMed Central, 2016)
    Background and objectives: Carbapenem-resistant Enterobacteriaceae (CRE) and other Gram-negative bacteria are among the most common pathogens responsible for both community and hospital acquired infection. The global spread ...
  • Colistin, Carbapenem and Cephalosporin-resistant Klebsiella pneumoniae reported from Misrata, Libya 

    Shallouf, Mohamed; Abrantes, Pedro Miguel dos Santos; Fielding, Burtram Clinton; Africa, Charlene Wilma Joyce (Medpharm Publications, 2017)
    Background: National surveillance of antimicrobial resistance has become a mandatory approach to control the spread of antimicrobial resistance and for the establishment of antibiotic treatment guidelines. In this study, ...
  • A comparison of susceptibility patterns of oral Candida isolates from South African and Cameroonian HIV- positive populations 

    Abrantes, Pedro Miguel dos Santos; McArthur, Carole P.; Africa, Charlene W.J. (The International Association for Dental Research (IADR), 2012)
    METHOD: In this study, Candida isolates were collected from the oral mucosa of 128 South African and 126 Cameroonian HIV-positive patients, by scraping the mouths of consenting patients using sterile cotton swabs. Ethics ...
  • Drug susceptibility profiles of Candida species isolated from the oral mucosa of HIV-positive West African patients using the TREK Sensititre system 

    McArthur, Carole P.; Abrantes, Pedro Miguel dos Santos; Awasom, Charles; Ayuk, L.; Africa, Charlene W.J. (2013)
    BACKGROUND: Candida infections are a common cause of death in immunocompromised patients. The prevalence and anti-mycotic drug susceptibility profiles of Candida species from Cameroon in Africa are unavailable. This ...
  • HIV/Candida co-infection in Sub-Saharan African women on ART 

    Abrantes, Pedro Miguel dos Santos; Africa, Charlene W.J. (Infectious Diseases Society of Southern Africa, the Sexually Transmitted Diseases Society of Southern and the Public Health Association of South Africa., 2013)
    INTRODUCTION: Sub-Saharan Africa has 23.5 million cases of HIV and is home to 92% of the world’s HIV-positive pregnant women of whom 24% die of pregnancy related complications. Oral candidiasis is a common condition in ...
  • Multi-drug resistant (MDR) oral Candida species isolated from HIV-positive patients in South Africa and Cameroon 

    Abrantes, Pedro Miguel dos Santos; McArthur, Carole P.; Africa, Charlene W.J. (Elsevier, 2014)
    Candida species are a common cause of infection in immune-compromised HIV-positive individuals, who are usually treated with the antifungal drug, fluconazole in public hospitals in Africa. However, information about the ...
  • Proteomic mechanisms of drug resistance in Candida cell membrane fractions 

    Abrantes, Pedro Miguel dos Santos; Bouic, Patrick J.D.; Africa, Charlene W.J. (International Association for Dental Research, 2014)
    INTRODUCTION: The African continent has the highest burden of HIV infection, accounting for approximately 65% of new infections globally. Oral candidiasis is a major cause of increased morbidity in HIV-infected individuals ...
  • Proteomics of drug-resistant HIV-associated candidiasis 

    Abrantes, Pedro Miguel dos Santos; Bouic, Patrick J.D.; Africa, Charlene W.J. (University of the Western Cape, 2015)
    Candidiasis and HIV co-infection may cause increased patient morbidity and mortality due to oropharyngeal or systemic dissemination. Limited information exists on the prevalence, antifungal susceptibility profiles and drug ...
  • Rare fungal species isolated from Libyan diabetic patients 

    Esmaio, Mustafa; Abrantes, Pedro Miguel dos Santos; Africa, Charlene W.J. (Infection Control Africa Network (ICAN), 2016)
    BACKGROUND AND OBJECTIVES: The emerging resistance of Candida species to antifungals routinely used to treat candidiasis in HIV patients and in patients with diabetes mellitus (DM) has resulted in the frequent isolation ...
  • Strengths and limitations of different Chromogenic Media for the identification of Candida species 

    Messeir, Ilze; Abrantes, Pedro Miguel dos Santos; Africa, Charlene W.J. (Scientific & Academic Publishing, 2012)
    The treatment of invasive candidiasis and other Candida infections with the appropriate antifungal agent is assisted by the identification of Candida isolates to the species level. Rapid and accurate methods of differentiation ...
  • Vitek characterisation of type 2 diabetes-associated Candida species 

    Esmaio, Mustafa Hassan Mustafa; Abrantes, Pedro Miguel dos Santos; Africa, Charlene Wilma Joyce (Elsevier, 2017)
    Background: Type 2 diabetes mellitus (T2DM) predisposes patients to opportunistic infections, such as invasive candidiasis. Treatment of candidiasis is challenged by the emerging resistance of Candida species. In this ...