Browsing Faculty of Dentistry by Author "Afrogheh, Amir H."
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Adenomatoid odontogenic tumour in the anterior mandible: a case report
Walters, J.; Shaik, Shoayeb; Afrogheh, Amir H. (Wiley-Blackwell, 2020)Adenomatoid odontogenic tumours are hamartomatous lesions that rarely deviate from their well-recognised radiological features. However, increasing numbers with atypical radiological features have been reported in recent ... -
Diffuse staining for activated NOTCH1 correlates with NOTCH1 mutation status and is associated with worse outcome in adenoid cystic carcinoma
Sajed, Dipti P.; Faquin, William C.; Carey, Chris; Severson, Eric A.; Afrogheh, Amir H.; Johnson, Carl A.; Blacklow, Stephen C.; Chau, Nicole G.; Lin, Derrick T.; Krane, Jeffrey F.; Jo, Vickie Y.; Garcia, Joaquín J.; Sholl, Lynette M.; Aster, Jon C. (Lippincott, Williams & Wilkins, 2017)NOTCH1 is frequently mutated in adenoid cystic carcinoma (ACC). To test the idea that immunohistochemical (IHC) staining can identify ACCs with NOTCH1 mutations, we performed IHC for activated NOTCH1 (NICD1) in 197 cases ... -
PD-L1 and PD-L2 expression levels are low in primary and secondary adenoid cystic carcinomas of the orbit: Therapeutic implications
Afrogheh, Amir H.; Wolkow, Natalie; Jakobiec, Frederick Albert (Wolters Kluwer Health, 2020)To determine if there is a biologic rationale for using checkpoint inhibitor drugs targeting programmed cell death ligand 1 (PD-L1) and PD-L2 in the treatment of adenoid cystic carcinoma of the orbit. Methods: Twenty-three ...