Browsing Research Articles (Medical Bioscience) by Title
Now showing items 45-64 of 108
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Genetic lesions within the 3a gene of SARS-CoV
(BioMed Central, 2005)A series of frameshift mutations within the 3a gene has been observed in culture-derived severe acute respiratory syndrome coronavirus (SARS-CoV). We report here that viral RNA from clinical samples obtained from SARS-CoV ... -
The genetic organisation of a 2,966 basepair DNA fragment of a Single Capsid Nucleopolyhedrovirus isolated from Trichoplusia ni
(Springer Verlag, 2002)In order to investiagte the genomic organization of the Trichoplusia ni Single Capsid Nucleoplyhedrovirus (TnSNPV) , a 2,966 base pairs (bp) genomic fragment was sequenced. The fragment was found to contain five open reading ... -
Group B streptococcus serotypes in pregnant women from the Western Cape region of South Africa
(Frontiers, 2018-12-04)Background: Maternal colonization of Group B streptococci (GBS) during pregnancy is an important risk factor for neonatal morbidity and mortality. The aim of this study was to determine the prevalence and serotype distribution ... -
HIV/Candida co-infection in Sub-Saharan African women on ART
(Infectious Diseases Society of Southern Africa, the Sexually Transmitted Diseases Society of Southern and the Public Health Association of South Africa., 2013)INTRODUCTION: Sub-Saharan Africa has 23.5 million cases of HIV and is home to 92% of the world’s HIV-positive pregnant women of whom 24% die of pregnancy related complications. Oral candidiasis is a common condition in ... -
Human coronavirus NL63 open reading frame 3 encodes a virion-incorporated N-glycosylated membrane protein
(BioMed Central, 2010)Background: Human pathogenic coronavirus NL63 (hCoV-NL63) is a group 1 (alpha) coronavirus commonly associated with respiratory tract infections. In addition to known non-structural and structural proteins all coronaviruses ... -
Human sperm handling in intracytoplasmic sperm injection processes: In vitro studies on mouse oocyte activation, embryo development competence and sperm oxidation–reduction potential
(Wiley, 2018)Polyvinylpyrrolidone (PVP) and hyaluronic acid (HA) are routinely used in handling spermatozoa for intracytoplasmic sperm injection (ICSI). As there are still concerns about possible adverse effects on the embryo, this ... -
Identification and characterization of microRNAs expressed in the African malaria vector Anopheles funestus life stages using high throughput sequencing
(BioMed Central, 2016)Background: Over the past several years, thousands of microRNAs (miRNAs) have been identified in the genomes of various insects through cloning and sequencing or even by computational prediction. However, the number of ... -
Identification and characterization of the Trichoplusia ni Single Capsid Nuclear Polyhedrosis Virus p10 gene
(Springer Verlag, 2000)The p10 gene was identified and characterized from the Trichoplusia ni single capsid nuclear polyhedrosis virus (TniSNPV). The p10 open reading frame (ORF) sequence was identified following sequencing of the ends of the ... -
Identification, sequence analysis, and phylogeny of the immediate early gene 1 of the trichoplusia ni single nucleocapsid polyhedrosis virus
(Springer Verlag, 2001)Substantial research has been conducted on the immediate early 1 (ie-1) genes from the prototype baculovirus Autographa californica multicapsid nuclear polyhedrosis virus (AcMNPV) and the Orgyia pseudotsugata multicapsid ... -
The impact of sperm DNA damage in assisted conception and beyond: recent advances in diagnosis and treatment
(Elsevier, 2013)Sperm DNA damage is a useful biomarker for male infertility diagnosis and prediction of assisted reproduction outcomes. It is associated with reduced fertilization rates, embryo quality and pregnancy rates, and higher ... -
The in vitro effects of artificial and natural sweeteners on the immune system using whole blood culture assays
(Taylor & Francis, 2013)This article investigates the effects of commercially available artificial (aspartame, saccharin, sucralose) and natural sweeteners (brown sugar, white sugar, molasses) on the immune system. Human whole blood cultures ... -
In vivo effects of eurycoma longifolia Jack (Tongkat Ali) extract on reproductive functions in the rat
(Blackwell, 2013)An aqueous extract of Eurycoma longifolia (Tongkat Ali; TA) roots is traditionally used to enhance male sexuality. Because previous studies are limited to only few sperm parameters or testosterone concentration, this study ... -
An in-depth bibliometric analysis and current perspective on male infertility research
(Korean Society for Sexual Medicine and Andrology, 2019)PURPOSE: Male infertility is emerging as a major, escalating global health problem that imposes the need to investigate research trends in male infertility. The purpose of this study is to analyze male infertility research ... -
An in-vitro analysis of the antimicrobial efficacy of herbal toothpastes on selected primary plaque colonizers
(iMD Publishers, 2011)Plaque associated oral disease affects a considerable portion of the population and is considered one of the major causes of tooth loss. In most cases toothbrushing only removes a limited amount of dental plaque and other ... -
Interpretation of semen analysis using WHO 1999 and WHO 2010 reference values: abnormal becoming normal
(Wiley, 2017)Reference values of WHO 1999 manual were used for the interpretation of semen analysis until 2010 when new reference values were introduced which have lower cut-off compared to WHO 1999. Therefore, several men who previously ... -
Interpretation of semen analysis using WHO 1999 and WHO 2010 reference values: Abnormal becoming normal
(Wiley, 2017)Reference values of WHO 1999 manual were used for the interpretation of semen analysis until 2010 when new reference values were introduced which have lower cut-off compared to WHO 1999. Therefore, several men who previously ... -
Is human Immunodeficiency Virus (HIV) stage an independent risk factor for altering the periodontal status of HIV-positive patients? A South African study
(BioMed Central, 2013)Background: The immunosuppresion in HIV patients makes them highly susceptible to microbial infections. The aim of the study was to establish whether HIV stage (as depicted by CD4+ T lymphocyte counts) could independently ... -
K21 compound, a potent antifungal agent: Implications for the treatment of fluconazole-resistant HIV-associated Candida species
(Frontiers, 2019-05-24)Background/objectives: With mucocutaneous candidiasis being highly prevalent in HIV patients, the emergence of fluconazole-resistant Candida species forms a major challenge in treating and eradicating these infections. The ... -
Life-long programming implications of exposure to tobacco smoking and nicotine before and soon after birth: Evidence for altered lung development
(MDPI, 2011)Tobacco smoking during pregnancy remains common, especially in indigenous communities, and likely contributes to respiratory illness in exposed offspring. It is now well established that components of tobacco smoke, notably ... -
MERS-CoV: Understanding the latest human coronavirus threat
(MDPI, 2018)Human coronaviruses cause both upper and lower respiratory tract infections in humans. In 2012, a sixth human coronavirus (hCoV) was isolated from a patient presenting with severe respiratory illness. The 60-year-old man ...
