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The African Coelecanth genome provides insights into tetrapod evolution
(Macmillan Publishers, 2013)
The discovery of a living coelacanth specimen in 1938 was remarkable, as this lineage of lobe-finned fish was thought to have become extinct 70 million years ago. The modern coelacanth looks remarkably similar to many of ...
A uniquely African focus: bioinformatics is a field that has grown exponentially in the past few years, and it is becoming increasingly important to collaborate as the field continues to gather momentum
(2015)
Bioinformatics is a field that has grown exponentially in the past few years, and it is becoming increasingly important to collaborate as the field continues to gather momentum.
Challenges of biobanking in South Africa to facilitate indigenous research in an environment burdened with human immunodeficiency virus, tuberculosis, and emerging non-communicable diseases
(Mary Ann Liebert, Inc., 2013)
The high burden of infectious diseases and the growing problem of noncommunicable and metabolic disease syndromes in South Africa (SA) forces a more focused research approach to facilitate cutting-edge scientific growth ...
Blood pressure gradients and cardiovascular risk factors in urban and rural populations in Abia State South Eastern Nigeria using the WHO STEPwise approach
(Public Library of Science, 2013)
Background: Developing countries of sub-Saharan Africa (SSA) face a double burden of non-communicable diseases (NCDs)
and communicable diseases. As high blood pressure (BP) is a common global cardiovascular (CV) disorder ...
Avihepadnavirus diversity in parrots is comparable to that found amongst all other avian species
(Elsevier, 2013)
Avihepadna viruses have previously been isolated from various species of duck ,goose, stork, heron and
crane. Recently the first parrot avihepadna virus was isolated from a Ring-necked Parakeet in Poland. In
this study, ...
The Influence of N-Linked Glycans on the MolecularDynamics of the HIV-1 gp120 V3 Loop
(PLoS ONE, 2013)
N-linked glycans attached to specific amino acids of the gp120 envelope trimer of a HIV virion can modulate the binding
affinity of gp120 to CD4, influence coreceptor tropism, and play an important role in neutralising ...
Characterizing the emergence and persistence of drug resistant mutations in HIV-1 subtype C infections using 454 ultra deep pyrosequencing
(BioMed Central -The Open Access Publisher, 2013)
BACKGROUND: The role of HIV-1 RNA in the emergence of resistance to antiretroviral therapies (ARTs) is well
documented while less is known about the role of historical viruses stored in the proviral DNA. The primary ...
A diverse array of genetic factors contribute to the pathogenesis of Systemic Lupus Erythematosus
(Biomed Central, 2013)
Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune disease with variable clinical presentation
frequently affecting the skin, joints, haemopoietic system, kidneys, lungs and central nervous system. It can ...
Extensive recombination detected among beak and feather disease virus isolates from breeding facilities in Poland
(Microbiology Society, 2013)
Beak and feather disease virus (BFDV) causes the highly contagious, in some cases fatal,
psittacine beak and feather disease in parrots. The European continent has no native parrots, yet
in the past has been one of the ...
Taste and odorant receptors of the coelecanth- a gene repertoire in transition
(Wiley, 2014)
G-protein coupled chemosensory receptors (GPCR-CRs) aid in the perception of odors and tastes in vertebrates. So far, six GPCR-CR families have been identified that are conserved in most vertebrate species. Phylogenetic ...