Now showing items 1-1 of 1

    • Deletion of IL-4Rα signalling on B cells limits hyperresponsiveness depending on antigen-load. 

      Hadebe, Sabelo; Khumalo, Jermaine; Mangali, Sandisiwe; Mthembu, Nontobeko; Ndlovu, Hlumani; Scibiorek, Martyna; Ngomti, Amkele; Brombacher, Frank (Elsevier, 2020)
      B cells play an important role in allergies through secretion of IgE. Interleukin 4 50 receptor α (IL-4Rα) is key in allergic asthma and regulates type 2 cytokine production, IgE 51 secretion and airway hyperresponsiveness ...