Browsing by Author "Leisegang, Kristian"
Now showing items 1-20 of 26
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Alternative medicine and herbal remedies in the treatment of erectile dysfunction: A systematic review
Leisegang, Kristian; Finelli, Renata (Informa UK Limited, trading as Taylor & Francis Group., 2021)Objectives: To systematically review and discuss the current evidence from placebo-controlled clinical trials that investigated the use of alternative medicines and herbal remedies in the management of erectile dysfunction ... -
A comparison between the anthropological and modern day uses of this indigenous herb
Leisegang, Kristian; Campbell, James; Ma, X; De Beer, Sanien (Conference: SA Medical Research Council 6th Annual Research Conference, 2012)Sceletium tortuosum (Fig. 1) is a scrambling succulent ground cover indigenous to the Western and Eastern Cape. It has probably been used for centuries as a mood-altering drug, especially by the Khoisan hunters and Nama ... -
Do lifestyle practices impede male fertility?
Leisegang, Kristian; Dutta, Sulagna (John Wiley & Sons, Inc, 2020)Alongside an increasing prevalence of couple and male infertility, evidence suggests there is a global declining trend in male fertility parameters over the past few decades. This may, at least in part, be explained ... -
The effect of Nigella sativa oil and metformin on male seminal parameters and testosterone in Wistar rats exposed to an obesogenic diet
Leisegang, Kristian; Almaghrawi, Walid; Henkel, Ralf (Elsevier, 2021)Obesity is a significant global health and socio-economic challenge, and considered an important risk factor for poor health outcomes including male reproductive dysfunction and infertility. As excess adiposity causes ... -
The effect of Nigella sativa oil and metformin on male seminal parameters and testosterone in Wistar rats exposed to an obesogenic diet
Leisegang, Kristian; Almaghrawi, Walid; Henkel, Ralf (Elsevier, 2020)Obesity is a significant global health and socio-economic challenge, and considered an important risk factor for poor health outcomes including male reproductive dysfunction and infertility. As excess adiposity causes ... -
Effect of the metabolic syndrome on male reproductive function: a case-controlled pilot study
Leisegang, Kristian; Bouic, Patrick J.D.; Henkel, Ralf (Wiley, 2014)The metabolic syndrome (MetS) is a constellation of various risk factors. This study aimed to investigate the effect of MetS on testosterone and progesterone, and semen parameters, in a case-controlled pilot study. Male ... -
The efficacy of zingiber officinale on dyslipidaemia, blood pressure, and inflammation as cardiovascular risk factors: A systematic review
Daniels, Chelsea Courtney; Isaacs, Zaiyaan; Leisegang, Kristian; Finelli, Renata (Clinical Nutrition ESPEN, 2022)Background & aims: Hypertension, dyslipidaemia, and chronic inflammation contribute to the development of cardiovascular disease (CVD). Zingiber officinale has been suggested to reduce these CVD risk factors; however, the ... -
A Global Survey of Reproductive Specialists to Determine the Clinical Utility of Oxidative Stress Testing and Antioxidant Use in Male Infertility
Leisegang, Kristian (The world journal of men's health, 2021)Globally, infertility impacts 15% of couples trying to conceive. The incidence of male infertility has been increasing over the past several decades, ranging from 20% to 70% worldwide [1,2]. The male partner is found to ... -
Impact of body composition analysis on male sexual function : A metabolic age study
Leisegang, Kristian; Henkel, Ralf; Majzoub, Ahmad; Elbardisi, Haitham; Madani, Sarah; Mahdi, Mohamed; Agarwal, Ashok; Khalafalla, Kareim; Alsaid, Sami; Arafa, Mohamed (Frontiers in Endocrinology, 2023-01)Metabolic Age (MetAge) and body composition analysis may reflect an individual’s metabolic status, which is believed to influence male sexual and gonadal functions. Although erectile dysfunction (ED) and hypogonadism are ... -
The impact of COVID-19 on the male reproductive tract and fertility: A systematic review
Sengupta, Pallav; Leisegang, Kristian; Agarwal, Ashok (Informa UK Limited, trading as Taylor & FrancisGroup., 2021)Objective: The COVID-19 pandemic, caused by the acute respiratory syndrome-coronavirus 2 (SARS-CoV-2), remains an ongoing public health challenge. Although males are affected slightly more than females, the impact of ... -
The impact of Covid-19 vaccines on male semen parameters: A retrospective cohort study
Henkel, Ralf; Leisegang, Kristian; Finelli, Renata (University of the Western Cape, 2023)The emergence of SARS-CoV-2 and the subsequent COVID-19 pandemic necessitated the development of adequate vaccines. Despite vaccines being demonstrated to be safe and effective for preventing severe disease and death, ... -
The impact of male overweight on semen quality and outcome of assisted reproduction
Leisegang, Kristian; Henkel, Ralf (Medknow Publications, 2014)The impact of obesity on male reproductive health remains a contested topic as evidence is inconclusive and inconsistent. Even more debatable is the effect of male obesity in assisted reproduction. In the manuscript, ... -
The Impact of Storage Time and Seasonal Harvesting on Levels of Sutherlandins and Sutherlandiosides in Lessertia frutescens
Leisegang, Kristian; Campbell, J; Weitz, F; Henkel, R.R (Conference: Faculty of Community and Health Sciences 2nd Research Day, 2013)In South Africa, an estimate of 70% of the population frequently uses traditional medicine for their health care needs. The use of Lessertia frutescens (Figure 1,2) by various cultural groups dates back to the earlier ... -
The in vitro modulation of steroidogenesis by inflammatory cytokines and insulin in TM3 Leydig cells
Leisegang, Kristian; Henkel, Ralf (BioMed Central, 2018)BACKGROUND: Cytokines and hormones, including insulin, are known to modulate the hypothalamic-pituitary-testes axis and steroidogenesis, both centrally and peripherally. In the context of chronic inflammation and hyper ... -
An in-depth bibliometric analysis and current perspective on male infertility research
Baskaran, Saradha; Agarwal, Ashok; Leisegang, Kristian; Peter, Natesan Pushparaj; Selvam, Manesh Kumar Panner; Henkel, Ralf (Korean Society for Sexual Medicine and Andrology, 2019)PURPOSE: Male infertility is emerging as a major, escalating global health problem that imposes the need to investigate research trends in male infertility. The purpose of this study is to analyze male infertility research ... -
Is there plagiarism in the most influential publications in the field of andrology?
Baskaran, Saradha; Henkel, Ralf; Leisegang, Kristian (Wiley, 2019)Plagiarism is a common form of academic misconduct that extensively jeopardises the quality of scientific publication. The purpose of this study is to determine the extent of plagiarism in the most influential andrology ... -
Male fertility and the COVID-19 pandemic: Systematic review of the literature
Leisegang, Kristian; Khalili, Mohammad Ali; Majzoub, Ahmad A. (Korean Society for Sexual Medicine and Andrology, 2020)Purpose: Since its discovery in December 2019, the novel coronavirus SARS-CoV-2 has spread globally, causing the current COVID-19 (coronavirus disease-19) pandemic. As there is an increase of infections in the male population, ... -
Nutritional value of cooked offal derived from free-range rams reared in South Africa
Hoffman, L.C.; Laubscher, L.L.; Leisegang, Kristian (Elsevier, 2013)Nutritional value of Dorper (n=10) and Merino (n=10) by-products were evaluated. Proximate composition differed between organs and breeds with Merino heart (68.9 g/100 g), spleen (77.2 g/100 g) and testicles (83.7 g/100 ... -
Obesity and metabolic syndrome associated with systemic inflammation and the impact on the male reproductive system
Leisegang, Kristian; Henkel, Ralf; Argarwal, Ashok (John Wiley & Sons Ltd, 2019)Obesity and metabolic syndrome (MetS) are global epidemics, driven by an obe‐sogenic environment. This is mediated by complex underlying pathophysiology, in which chronic inflammation is an important aetiological and ... -
Obesity is associated with increased seminal insulin and leptin alongside reduced fertility parameters in a controlled male cohort
Leisegang, Kristian; Menkveld, Roelof; Bouic, Patrick J.D.; Henkel, Ralf (BioMed Central, 2014)Obesity appears to be associated with male reproductive dysfunction and infertility, although this has been inconsistent and inconclusive. Insulin and leptin are known mediators and modulators of the hypothalamus-pituitary-testes ...