Browsing Faculty of Natural Sciences by Title
Now showing items 160-179 of 2571
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Assessment of thermal and hydrolytic stabilities and aqueous solubility of artesunate for formulation studies
(AAPS PharmSciTech, 2023)For the purpose of establishing the optimum processing parameters and storage conditions associated with nanolipid formulations of the artemisinin derivative artesunate, it was necessary to evaluate the thermal stability ... -
Assessment of Vancomycin Pharmacokinetics and Dose Regimen Optimisation in Preterm Neonates
(Springer Nature, 2020)The pharmacokinetics of vancomycin, a drug used for the treatment of methicillin-resistant Staphylococcus aureus (MRSA), varies between paediatric and adult patients. The objective of this study was to assess the ... -
Associated risk factors of STIs and multiple sexual relationships among youths in Malawi
(PLoS, 2015)Having unprotected sex with multiple sexual partners (MSP) is the greatest risk factor for human immunodeficiency virus (HIV) and other sexually transmitted infections (STIs) among youths. Young people with MSPs are less ... -
Association among sperm chromatin condensation, sperm DNA fragmentation and 8-OHdG in seminal plasma and semen parameters in infertile men with oligoasthenoteratozoospermia
(Wiley, 2021)The present study aimed to investigate the clinical role of standard sperm diagnosis parameters (sperm concentration, motility, morphology) as well as aniline blue staining of histones, 8-OHdG, TUNEL assay were performed ... -
Association analysis of two single-nucleotide polymorphisms of the RELN gene with autism in the South African population
(Mary Ann Liebert, Inc., 2013)BACKGROUND: Autism (MIM209850) is a neurodevelopmental disorder characterized by a triad of impairments, namely impairment in social interaction, impaired communication skills, and restrictive and repetitive behavior. A ... -
The association between environmental exposures during childhood and the subsequent development of Crohn's Disease: A score analysis approach
(Public Library of Science, 2017)Background Environmental factors during childhood are thought to play a role in the aetiology of Crohn's Disease (CD). In South Africa, recently published work based on an investigation of 14 childhood environmental exposures ... -
The association between gender and tooth loss in a small rural population of South Africa
(Science Publishing Group, 2013)Periodontal disease, which attacks the gums and supporting structures of the tooth, is one of the major causes of tooth loss in adults. Few studies on general well-being have compared the differences in oral health between ... -
Association between pro-inflammatory alleles and allergic phenotypes in Xhosa adolescents
(Wiley, 2018)BACKGROUND: Significant differences exist in the prevalence, spectrum, and severity of allergic diseases between developing and developed countries and between subpopulations within single countries. These discrepancies ... -
Association between promoter methylation of MLH1 and MSH2 and reactive oxygen species in oligozoospermic men—A pilot study
(Wiley, 2017)MLH1 and MSH2 are important genes for DNA mismatch repair and crossing over during meiosis and are implicated in male infertility. Therefore, the methylation patterns of the DNA mismatch repair genes MLH1 and MSH2 in ... -
Association between socio-economic factors and HIV self-testing knowledge amongst South African women
(AOSIS, 2022)Self-testing for HIV is an effective and alternative method of increasing HIV testing rates and a strategy for reaching populations that are underserved by HIV testing services. Nonetheless, many resource-constrained ... -
The association of mthfr (rs1801133) with hypertension in an indigenous South African population
(Frontiers Media, 2022)The current study sought to investigate the association between the methylenetetrahydrofolate reductase (MTHFR) variant (rs1801133) and the risk of developing hypertension (HTN) in an indigenous South African population.A ... -
Association of XRCC1 and ERCC2 promoters’ methylation with chromatin condensation and sperm DNA fragmentation in idiopathic oligoasthenoteratozoospermic men
(Blackwell Publishing Ltd, 2021)The aim of the study was to investigate whether the promoter methylation of XRCC1 and ERCC2 genes is associated with sperm DNA fragmentation and chromatin condensation in idiopathic oligoasthenoteratozoospermic men. This ... -
Associations between human leukocyte antigen class I variants and the Mycobacterium tuberculosis subtypes causing disease
(Oxford University Press, 2013)BACKGROUND. The development of active tuberculosis disease has been shown to be multifactorial. Interactions between host and bacterial genotype may influence disease outcome, with some studies indicating the adaptation ... -
Asteroseismology of Massive Stars with the TESS Mission: The Runaway β Cep Pulsator PHL 346 = HN Aqr
(The Astrophysical journal letter, 2019)We report an analysis of the first known β Cep pulsator observed by the Transiting Exoplanet Survey Satellite (TESS) mission, the runaway star PHL 346 = HN Aqr. The star, previously known as a singly periodic pulsator, has ... -
Astronomy for Development – A story from South Africa
(UWC, 2021)In this article we describe the recent history of astronomy in South Africa from the perspective of development. We describe how all major astronomy initiatives have carried a component of development with them, be it ... -
Asynchronous video telephony for the Deaf
(Telkom, 2007)The South African Deaf community has very limited telephony options. They prefer to communicate in sign language, a visual medium. Realtime video over Internet Protocol is a promising option, but in reality, the quality ... -
Atmospheric bromoform at Cape Point, South Africa: an initial fixed-point data set on the African continent
(EGU, 2018)Bromoform mixing ratios in marine air were measured at Cape Point Global Atmospheric Watch Station, South Africa. This represents the first such bromoform data set recorded at this location. Manual daily measurements were ... -
Attenuation of hyperglycemia-associated dyslipidemic, oxidative, cognitive, and inflammatory crises via modulation of neuronal ChEs/NF-κB/COX-2/NOx, and hepatorenal functional deficits by the Tridax procumbens extract
(Elsevier, 2023)Tridax procumbens (cotton buttons) is a flowering plant with a medicinal reputation for treating infections, wounds, diabetes, and liver and kidney diseases. The present research was conducted to evaluate the possible ... -
Augmenting machine learning photometric redshifts with Gaussian mixture models
(Oxford University Press, 2020-09-11)Wide-area imaging surveys are one of the key ways of advancing our understanding of cosmology, galaxy formation physics, and the large-scale structure of the Universe in the coming years. These surveys typically require ... -
Austral winter marine epilithic diatoms: Community composition and distribution on intertidal rocky substrate around the coast of South Africa
(Elsevier, 2020)The knowledge on the composition and spatial distribution of marine benthic diatoms around the coast of South Africa remains limited. Epilithic diatom assemblages from natural intertidal rocky substrate and physico-chemical ...