Browsing Faculty of Natural Sciences by Author "Africa, Charlene Wilma Joyce"
Now showing items 1-13 of 13
-
Biosynthesis, Characterization, and Biological Activities of Procyanidin Capped Silver Nanoparticles
Badeggi, Umar M.; Badmus, Jelili A.; Botha, Subelia S.; Ismail, Enas; Marnewick, Jeanine L.; Africa, Charlene Wilma Joyce; Hussein, Ahmed A. (Multidisciplinary Digital Publishing Institute, 2020-09-19)In this study, procyanidin dimers and Leucosidea sericea total extract (LSTE) were employed in the synthesis of silver nanoparticles (AgNPs) and characterized by ultraviolet-visible (UV-Visible) spectroscopy, high-resolution ... -
Candida species carriage in diabetic patients in Misrata, Libya
Esmaio, Mustafa Hassan Mustafa; Abrantes, Pedro Miguel dos Santos; Africa, Charlene Wilma Joyce (Medpharm Publications, 2017)Background: There is a paucity of studies describing the prevalence and antimicrobial profiles of Candida in Libya. Limited treatment choices in the antifungal armamentarium in public healthcare settings in Africa require ... -
Colistin, Carbapenem and Cephalosporin-resistant Klebsiella pneumoniae reported from Misrata, Libya
Shallouf, Mohamed; Abrantes, Pedro Miguel dos Santos; Fielding, Burtram Clinton; Africa, Charlene Wilma Joyce (Medpharm Publications, 2017)Background: National surveillance of antimicrobial resistance has become a mandatory approach to control the spread of antimicrobial resistance and for the establishment of antibiotic treatment guidelines. In this study, ... -
Group B streptococcus serotypes in pregnant women from the Western Cape region of South Africa
Africa, Charlene Wilma Joyce; Kaambo, Eveline (Frontiers, 2018-12-04)Background: Maternal colonization of Group B streptococci (GBS) during pregnancy is an important risk factor for neonatal morbidity and mortality. The aim of this study was to determine the prevalence and serotype distribution ... -
HPLC-MS identification and expression of Candida drug-resistance proteins from African HIV-infected patients
Abrantes, Pedro Miguel dos Santos; Fisher, Randall; Bouic, Patrick J D; McArthur, Carole P; Fielding, Burtram C; Africa, Charlene Wilma Joyce (AIMS Press, 2021-09-10)The objective of this study was to elucidate the proteomic mechanisms of drug resistance in HIV-infected African patients. Cell membrane fractions from forty oral Candida isolates isolated from African HIV-positive patients ... -
Is human immunodeficiency virus (HIV) stage an independent risk factor for altering the periodontal status of HIV-positive patients? A South African study
John, Cathy Nisha; Stephen, Lawrence Xavier; Africa, Charlene Wilma Joyce (BMC, 2013)The immunosuppresion in HIV patients makes them highly susceptible to microbial infections. The aim of the study was to establish whether HIV stage (as depicted by CD4+ T lymphocyte counts) could independently be associated ... -
K21 compound, a potent antifungal agent: Implications for the treatment of fluconazole-resistant HIV-associated Candida species
John, Cathy Nisha; Abrantes, Pedro Miguel dos Santos; Prusty, Bhupesh; Ablashi, Dharam; Africa, Charlene Wilma Joyce (Frontiers, 2019-05-24)Background/objectives: With mucocutaneous candidiasis being highly prevalent in HIV patients, the emergence of fluconazole-resistant Candida species forms a major challenge in treating and eradicating these infections. The ... -
Measuring Streptococcus mutans, Streptococcus sanguinis and Candida albicans biofilm formation using a real-time impedance-based system
Abrantes, Pedro Miguel dos Santos; Africa, Charlene Wilma Joyce (Elsevier, 2019-12-20)Candida albicans and streptococci are amongst the most common fungal and bacterial organisms present in the oral cavity, with a growing body of evidence implicating C. albicans in increased caries severity and in ... -
Oral health status and treatment needs of pregnant women attending antenatal clinics in KwaZulu-Natal, South Africa
Africa, Charlene Wilma Joyce; Turton, Mervyn (Hindawi, 2019)During pregnancy, the oral cavity is characterised by an acidic environment and an inflammatory response brought about by vomiting and changes in hormonal levels, respectively, thereby increasing the mother’s risk of ... -
A population model for the 2017/18 listeriosis outbreak in South Africa
Witbooi, Peter Joseph; Africa, Charlene Wilma Joyce; Christoffels, Alan; Ahmed, Ibrahim Hussin Ibrahim (PLoS One, 2020-03-12)We introduce a compartmental model of ordinary differential equations for the population dynamics of listeriosis, and we derive a model for analysing a listeriosis outbreak. The model explicitly accommodates neonatal ... -
Real-time assessment of Candida biofilm disruption by Galenia africana
Stuurman, Keith; Abrantes, Pedro Miguel dos Santos; Klaasen, Jeremy; Africa, Charlene Wilma Joyce (2022-05-25)Candida species often cause opportunistic infections in immunocompromised patients and are able to form highly structured biofilms that protect the yeast cells from the external environment and the action of antimicrobials. ... -
Real-time assessment of Candida biofilm formation
Abrantes, Pedro Miguel dos Santos; Behardien, Kauthar; Africa, Charlene Wilma Joyce (Elsevier, 2021-09)Background: Candida infections are responsible for increased morbidity and mortality in immunocompromised patients, particularly when the Candida biofilm is composed of drug-resistant species. Although the biofilm formation ... -
Vitek characterisation of type 2 diabetes-associated Candida species
Esmaio, Mustafa Hassan Mustafa; Abrantes, Pedro Miguel dos Santos; Africa, Charlene Wilma Joyce (Elsevier, 2017)Background: Type 2 diabetes mellitus (T2DM) predisposes patients to opportunistic infections, such as invasive candidiasis. Treatment of candidiasis is challenged by the emerging resistance of Candida species. In this ...