Browsing Faculty of Natural Sciences by Author "Kaur, Mandeep"

Now showing items 1-5 of 5

    • Association analysis of two single-nucleotide polymorphisms of the RELN gene with autism in the South African population 

      Sharma, Jyoti Rajan; Arieff, Zainunisha; Gameeldien, Hajirah; Davids, Muneera; Kaur, Mandeep; van der Merwe, Lize (Mary Ann Liebert, Inc., 2013)
      BACKGROUND: Autism (MIM209850) is a neurodevelopmental disorder characterized by a triad of impairments, namely impairment in social interaction, impaired communication skills, and restrictive and repetitive behavior. A ...

    • DDEC: Dragon databaseof genes implicated in esophageal cancer 

      Essack, Magbubah; Radovanovic, Aleksander; Schaefer, Ulf; Schmeier, Sebastian; Seshadri, Sundararajan V.; Christoffels, Alan; Kaur, Mandeep; Bajic, Vladimir B. (BioMed Central, 2009)
      Esophageal cancer ranks eighth in order of cancer occurrence. Its lethality primarily stems from inability to detect the disease during the early organ-confined stage and the lack of effective therapies for advanced-stage ...

    • DDESC: Dragon database for exploration of sodium channels in human 

      Sagar, Sunil; Kaur, Mandeep; Dawe, Adam; Seshadri, Sundararajan V.; Christoffels, Alan; Schaefer, Ulf; Radovanovic, Aleksander; Bajic, Vladimir B. (BMC Cancer, 2008)
      Sodium channels are heteromultimeric, integral membrane proteins that belong to a superfamily of ion channels. The mutations in genes encoding for sodium channel proteins have been linked with several inherited genetic ...

    • DDPC: Dragon database of genes associated with prostate cancer 

      Maqungo, Monique; Kaur, Mandeep; Kwofie, Samuel K.; Radovanovic, Aleksander; Schaefer, Ulf; Schmeier, Sebastian; Oppon, Ekow; Christoffels, Alan; Bajic, Vladimir B. (Oxford Journals, 2011)
      Prostate cancer (PC) is one of the most commonly diagnosed cancers in men. PC is relatively difficult to diagnose due to a lack of clear early symptoms. Extensive research of PC has led to the availability of a large amount ...

    • Hypertension in African populations: Review and computational insights 

      Mabhida, Sihle E.; Mashatola, Lebohang; Kaur, Mandeep (MPDI, 2021)
      Hypertension (HTN) is a persistent public health problem affecting approximately 1.3 billion individuals globally. Treatment-resistant hypertension (TRH) is defined as high blood pressure (BP) in a hypertensive patient ...