Now showing items 19-22 of 22

  • The search for the ideal biocatalyst 

    Burton, Stephanie; Cowan, Donald A.; Woodley, John M. (Nature Publishing Group, 2002)
    While the use of enzymes as biocatalysts to assist in the industrial manufacture of fine chemicals and pharmaceuticals has enormous potential, application is frequently limited by evolution-led catalyst traits. The advent ...
  • Sequence analysis of an Archaeal virus isolated from a hypersaline lake in Inner Mongolia, China 

    Pagaling, Eulyn; Haigh, Richard D.; Grant, William D.; Cowan, Donald A.; Jones, Brian; Ma, Yanhe; Ventosa, Antonio; Heaphy, Shaun (BioMed Central, 2007)
    Background: We are profoundly ignorant about the diversity of viruses that infect the domain Archaea. Less than 100 have been identified and described and very few of these have had their genomic sequences determined. ...
  • Structure of an aliphatic amidase from Geobacillus pallidus RAPc8 

    Kimani, Serah W.; Agarkar, Vinod B.; Cowan, Donald A.; Sayed, Muhammed F.; Sewell, B. Trevor (International Union of Crystallography, 2007)
    The amidase from Geobacillus pallidus RAPc8, a moderate thermophile, is a member of the nitrilase superfamily and catalyzes the conversion of amides to the corresponding carboxylic acids and ammonia. It shows both ...
  • The upper temperature for life – where do we draw the line? 

    Cowan, Donald A. (Elsevier, 2004)
    The newly isolated hyperthermophilic archaeal strain 121 grows slowly at 121 8C and even survives short periods at 130 8C. This is another organism that grows best at temperatures well in excess of 100 8C! We should not ...