Browsing Research Articles (Medical Bioscience) by Issue Date
Now showing items 61-80 of 256
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The effectiveness of sewage treatment processes to remove faecal pathogens and antibiotic residues
(TAYLOR & FRANCIS INC, 2013)Pathogens and antibiotics enter the aquatic environment via sewage effluents and may pose a health risk to wild life and humans.The aim of this study was to determine the levels of faecal bacteria, and selected antibiotic ... -
Reconstruction of major maternal and paternal lineages of the Cape Muslim population
(Sociedade Brasileira de Genética, 2013)The earliest Cape Muslims were brought to the Cape (Cape Town - South Africa) from Africa and Asia from 1652 to 1834. They were part of an involuntary migration of slaves, political prisoners and convicts, and they ... -
The Coronavirus Nucleocapsid is a Multifunctional Protein
(MDPI, 2014)The coronavirus nucleocapsid (N) is a structural protein that forms complexes with genomic RNA, interacts with the viral membrane protein during virion assembly and plays a critical role in enhancing the efficiency of virus ... -
Effect of Cissampelos capensis rhizome extract on human spermatozoa in vitro
(Wiley, 2014)Cissampelos capensis is commonly known by the Afrikaans name ‘dawidjies’ or ‘dawidjieswortel’. C. capensis is the most important and best-known medicinal plant of the family Menispermaceae used by the Khoisan and other ... -
Proteomic mechanisms of drug resistance in Candida cell membrane fractions
(International Association for Dental Research, 2014)INTRODUCTION: The African continent has the highest burden of HIV infection, accounting for approximately 65% of new infections globally. Oral candidiasis is a major cause of increased morbidity in HIV-infected individuals ... -
Anaerobes and bacterial vaginosis in pregnancy: virulence factors contributing to vaginal colonisation
(Multidisciplinary Digital Publishing Institute, 2014)The aetiology and pathogenesis of bacterial vaginosis (BV) is unclear but it appears to be associated with factors that disrupt the normal acidity of the vagina thus altering the equilibrium between the normal vaginal ... -
Multi-drug resistant (MDR) oral Candida species isolated from HIV-positive patients in South Africa and Cameroon
(Elsevier, 2014)Candida species are a common cause of infection in immune-compromised HIV-positive individuals, who are usually treated with the antifungal drug, fluconazole in public hospitals in Africa. However, information about the ... -
Additive antibacterial activity of naringenin and antibiotic combinations against multidrug resistant Staphylococcus aureus
(Academic Journals, 2015)Methicillin-resistant Staphylococcus aureus has been causing numerous problems in the health care sector. This is mainly due to its ability to develop resistance to a number of antibiotics used to treat staphylococcal ... -
Bibliometrics: tracking research impact by selecting the appropriate metrics
(Medknow Publications, 2016)Traditionally, the success of a researcher is assessed by the number of publications he or she publishes in peer-reviewed, indexed, high impact journals. This essential yardstick, often referred to as the impact of a ... -
Unlocking community capabilities across health systems in low- and middle-income countries: lessons learned from research and reflective practice
(BioMed Central, 2016)The right and responsibility of communities to participate in health service delivery was enshrined in the 1978 Alma Ata declaration and continues to feature centrally in health systems debates today. Communities are a ... -
Odontogenic myxoma: a clinicopathological study in a South African population
(Blackwell, 2016)Background: Odontogenic myxoma is a benign, locally aggressive neoplasm of the jaws. Prevalence rates range between 0.5% and 17.7% of odontogenic tumours. There are few reports in the literature on this lesion in African ... -
Identification and characterization of microRNAs expressed in the African malaria vector Anopheles funestus life stages using high throughput sequencing
(BioMed Central, 2016)Background: Over the past several years, thousands of microRNAs (miRNAs) have been identified in the genomes of various insects through cloning and sequencing or even by computational prediction. However, the number of ... -
Accuracy of magnetic resonance imaging in detecting lumbo-sacral nerve root compromise: A systematic literature review
(BioMed Central, 2016)Background: MRI is considered to be the diagnostic tool of choice in diagnosing nerve root compromise among patients presenting with clinical suspicion of lumbo-sacral radiculopathy. There exists controversy among researchers ... -
Use of a rat ex-vivo testis culture method to assess toxicity of select known male reproductive toxicants
(Elsevier, 2016)Due to the complex physiology of the testes, in vitro models have been largely unsuccessful at modeling testicular toxicity in vivo. We conducted a pilot study to evaluate the utility of the Durand ex vivo rat seminiferous ... -
Autoimmune progesterone dermatitis: Case report with history of urticaria, petechiae and palpable pinpoint purpura triggered by medical abortion
(South African Medical Association, 2016)Autoimmune progesterone dermatitis (APD) is a rare autoimmune response to raised endogenous progesterone levels that occur during the luteal phase of the menstrual cycle. Cutaneous, mucosal lesions and other systemic ... -
Determination of seminal oxidation–reduction potential (ORP) as an easy and cost-effective clinical marker of male infertility
(Wiley, 2017)Oxidative stress (OS) is an important contributing factor to male infertility. While previous methods to measure seminal OS are time-consuming and limited to the use of freshly produced semen, oxidation reduction potential ... -
Association between promoter methylation of MLH1 and MSH2 and reactive oxygen species in oligozoospermic men—A pilot study
(Wiley, 2017)MLH1 and MSH2 are important genes for DNA mismatch repair and crossing over during meiosis and are implicated in male infertility. Therefore, the methylation patterns of the DNA mismatch repair genes MLH1 and MSH2 in ... -
Molecular detection of tick-borne pathogen diversities in ticks from livestock and reptiles along the shores and adjacent islands of lake Victoria and lake Baringo, Kenya
(Frontiers Media, 2017)Tick-borne pathogens (TBPs) are responsible for some of the most serious emerging infectious diseases facing sub-Saharan Africa (SSA) and the rest of the world today (1, 2). In Kenya, TBPs (including viral diseases—arboviruses) ... -
The threat of aerobic vaginitis to pregnancy and neonatal morbidity
(Women's Health and Action Research Centre, 2017)Aerobic vaginitis (AV) is an endogenous opportunistic infection brought about by the disruption of the normal vaginal microbiota. Its early diagnosis and treatment during pregnancy may reduce the risk of negative pregnancy ... -
Candida antifungal drug resistance in sub-Saharan African populations: A systematic review
(Science Navigation Group, 2017)BACKGROUND: Candida infections are responsible for increased morbidity and mortality rates in at-risk patients, especially in developing countries where there is limited access to antifungal drugs and a high burden of HIV ...