Search
Now showing items 21-30 of 58
Carbonic anhydrase II based biosensing of carbon dioxide at high temperature: an analytical and MD simulation study
(OMICS International, 2018)
Concentration of carbon dioxide (CO2) in the atmosphere has increased significantly due to anthropogenic
activities and attributed as a major factor to global warming. Its detection by biosensing methods will provide ...
Selecting an appropriate method for expressing S locus F-box-S2 recombinant protein
(Elsevier, 2017)
A single locus (S locus) including at least two linked genes (female and male determinants) genetically controls
the gametophytic self-incompatibility (GSI) in apple, which has evolved to avoid self-fertilization. There ...
Whole-genome sequencing for an enhanced understanding of genetic variation among South Africans
(Nature Publishing Group, 2017)
The Southern African Human Genome Programme is a national initiative that aspires to
unlock the unique genetic character of southern African populations for a better understanding
of human genetic diversity. In this pilot ...
A 35-gene signature discriminates between rapidly- and slowly-progressing glioblastoma multiforme and predicts survival in known subtypes of the cancer
(BioMed Central, 2018)
BACKGROUND: Gene expression can be employed for the discovery of prognostic gene or multigene signatures
cancer. In this study, we assessed the prognostic value of a 35-gene expression signature selected by pathway ...
Hackathons as a means of accelerating scientific discoveries and knowledge transfer
(Cold Spring Harbor Laboratory Press, 2018)
Scientific research plays a key role in the advancement of human knowledge and pursuit of solutions to important societal
challenges. Typically, research occurs within specific institutions where data are generated and ...
A meta-analysis of public microarray data identifies gene regulatory pathways deregulated in peripheral blood mononuclear cells from individuals with Systemic Lupus Erythematosus compared to those without
(BioMed Central, 2017)
BACKGROUND: Systemic Lupus Erythematosus (SLE) is a complex, multi-systemic, autoimmune disease for which the
underlying aetiological mechanisms are poorly understood. The genetic and molecular processes underlying ...
Analyses of HIV-1 integrase sequences prior to South African national HIV-treatment program and available of integrase inhibitors in Cape Town, South Africa
(Nature Publishing Group, 2018)
HIV-Integrase (IN) has proven to be a viable target for highly specific HIV-1 therapy. We aimed to
characterize the HIV-1 IN gene in a South African context and identify resistance-associated mutations
(RAMs) against ...
Castleman’s disease in the HIV-endemic setting
(Dovepress, 2018)
Castleman’s disease (CD), first described by Benjamin Castleman in 1954, is a
giant or angiofollicular lymph node hyperplasia, described as a rare monotypic polyclonal B-cell
lymphoproliferative disorder with an incompletely ...
Effectiveness of sms technology on timely community health worker follow-up for childhood malnutrition: A retrospective cohort study in sub-Saharan Africa
(U.S. Agency for International Development, 2018)
The Millennium Villages Project facilitated technology-based health interventions in rural under-resourced areas of subSaharan Africa. Our study examined whether data entry using SMS compared with paper forms by community ...
Chromosomal-level assembly of the Asian seabass genome using long sequence reads and multi-layered scaffolding
(Public Library of Science, 2016)
We report here the ~670 Mb genome assembly of the Asian seabass (Lates calcarifer), a
tropical marine teleost. We used long-read sequencing augmented by transcriptomics, optical
and genetic mapping along with shared ...