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Inhibiting CDK6 activity by quercetin is an attractive strategy for cancer therapy
(American Chemical Society, 2020)
Cyclin-dependent kinase 6 (CDK6) is a potential drug target that plays an important role in the progression of different types of cancers. We performed in silico and in vitro screening of different natural compounds and ...
Corrigendum: Synthesis and cytotoxic activity of novel indole derivatives and their in silico screening on spike glycoprotein of sars-cov-2
(Frontiers Media, 2021)
The authors Kaliappillai Vijayakumar, Magda H. Abdellattif, Mohd Shahbaaz were not included in the published article and the authors Daoud Ali, Saud Alarifi, and Amal Alotaibi were mistakenly included in the author list. ...
Synthesis of oxygen deficient tio2 for improved photocatalytic efficiency in solar radiation
(MDPI, 2021)
The photocatalytic activities of TiO2 have been limited mainly to absorbing in the ultraviolet
spectrum which accounts for only 5% of solar radiation. High energy band gap and electron
recombination in TiO2 nanoparticles ...
Antennal enriched odorant binding proteins are required for odor communication in glossina f. Fuscipes
(MPDI, 2021)
Olfaction is orchestrated at different stages and involves various proteins at each step.
For example, odorant-binding proteins (OBPs) are soluble proteins found in sensillum lymph that
might encounter odorants before ...
Transcriptomic profile of mycobacterium smegmatis in response to an imidazo[1,2-b][1,2,4,5]tetrazine reveals its possible impact on iron metabolism
(Frontiers Media, 2021)
Tuberculosis (TB), caused by the Mycobacterium tuberculosis complex bacteria, is
one of the most pressing health problems. The development of new drugs and
new therapeutic regimens effective against the pathogen is one ...
Current perspectives in the discovery of newer medications against the outbreak of Covid-19
(Frontiers Media, 2021)
A rapid and increasing spread of COVID-19 pandemic disease has been perceived
worldwide in 2020. The current COVID-19 disease outbreak is due to the spread of
SARS-CoV-2. SARS-CoV-2 is a new strain of coronavirus that ...
Functional and structural analysis of predicted proteins obtained from homo sapiens' minisatellite 33.15-tagged transcript pAKT-45 variants
(Hindawi, 2020)
The spermatozoa are transcriptionally dormant entities which have been recognized to be an archive of mRNA, coding for a variety of functionally crucial cellular proteins. This significant repository of mRNA is predicted ...
Cellular and molecular targets of waterbuck repellent blend odors in antennae of glossina fuscipes fuscipes newstead, 1910
(Frontiers Media S.A., 2020)
Insects that transmit many of the world’s deadliest animal diseases, for instance
trypanosomosis, find their suitable hosts and avoid non-preferred hosts mostly through
olfactory cues. The waterbuck repellent blend (WRB) ...
A novel nano therapeutic using convalescent plasma derived exosomal (CPExo) for Covid-19: A combined hyperactive immune modulation and diagnostics
(Elsevier, 2021)
Extracellular vesicles like exosomes are important therapeutic tactics for treating COVID -19. By utilizing
convalescent plasma derived exosomes (CPExo) from COVID-19 recovered persistence could accelerate the
treatment ...
In silico repurposing of a Novobiocin derivative for activity against latency associated Mycobacterium tuberculosis drug target nicotinate-nucleotide adenylyl transferase (Rv2421c)
(Public Library of Science, 2021)
Nicotinamide-nucleotide adenylyl transferase (Rv2421c) was selected as a potential drug
target, because it has been shown, in vitro, to be essential for Mycobacterium tuberculosis
growth. It is conserved between mycobacterium ...