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HIV-1 diversity and the implementation of integrase strand-transfer inhibitors as part of combination antiretroviral therapy
(SAMA, 2020)
: The integrase (IN) strand-transfer inhibitor (InSTI)
dolutegravir (DTG) is now recommended by the World Health
Organization as part of salvage and/or first-line combination
antiretroviral therapy (cART).[1] DTG has a ...
New palladium(II) and platinum(II) complexes based on pyrrole Schiff bases: synthesis, characterization, X-ray structure, and anticancer activity
(American Chemical Society, 2020)
New palladium (Pd)II and platinum (Pt)II complexes (C1−C5) from the Schiff
base ligands, R-(phenyl)methanamine (L1), R-(pyridin-2-yl)methanamine (L2), and R-(furan2-yl)methanamine (L3) (R-(E)-N-((1H-pyrrol-2-yl) methylene)) ...
Pre-race screening and stratification predicts adverse events—A 4-year study in 29585 ultra-marathon entrants, SAFER X
(Wiley-Blackwell, 2020)
Pre-race screening and risk stratification in recreational endurance runners may predict adverse events (AEs) during a race. Aim: To determine if pre-race screening and risk stratification predict AEs during a race. Methods: ...
The evolving role of science in society
(José Frantz, 2020)
The world is experiencing a traumatic change brought about by the Covid-19 pandemic. It is traumatic because it is sudden and affects everyone around the globe at once. Nothing like this has ever happened so rapidly before, ...
Erratum: The frequency of very young galaxies in the local Universe: II. The view from SDSS spectra
(Oxford University Press, 2020)
Only a handful of galaxies in the local Universe appear to be very young. We estimate the
fraction of very young galaxies (VYGs), defined as those with more than half their stellar
masses formed within the last Gyr. We ...
Big data analytics and its role to support groundwater management in the Southern African development community
(MDPI, 2020)
Big data analytics (BDA) is a novel concept focusing on leveraging large volumes of
heterogeneous data through advanced analytics to drive information discovery. This paper aims to
highlight the potential role BDA can ...
Do lifestyle practices impede male fertility?
(John Wiley & Sons, Inc, 2020)
Alongside an increasing prevalence of couple and male infertility, evidence suggests
there is a global declining trend in male fertility parameters over the past few decades.
This may, at least in part, be explained ...
Neuroprotective activities of Boophone haemanthoides (amaryllidaceae) extract and its chemical constituents
(Multidisciplinary Digital Publishing Institute (MDPI), 2020)
Parkinson’s disease (PD) is a neurodegenerative condition that progresses as age increases, and some of its major symptoms include tremor and postural and movement-related difficulties. To date, the treatment of PD remains ...
A retrospective descriptive investigation of adult patients receiving third-line antiretroviral therapy in the North West province, South Africa
(Makerere University, 2020)
Greater access and prolonged exposure to ART may inevitably lead to more treatment failure and increase the need for third-line ART (TLART) in a resource-limited setting. Objective: To describe characteristics and resistance ...
A fitted operator method for a model arising in vascular tumor dynamics
(Tianjin Polytechnic University, 2020)
In this paper, we consider a model for the population kinetics of human tumor cells in vitro, differentiated
by phases of the cell division cycle and length of time within each phase. Since it is not easy to isolate ...