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A retrospective descriptive investigation of adult patients receiving third-line antiretroviral therapy in the North West province, South Africa
(Makerere University, 2020)
Greater access and prolonged exposure to ART may inevitably lead to more treatment failure and increase the need for third-line ART (TLART) in a resource-limited setting. Objective: To describe characteristics and resistance ...
Meningitis during COVID -19 pandemic in the Democratic Republic of Congo: A call for concern
(Elsevier, 2022-01-01)
Meningitis is a severe infection and a significant public health challenge. The meningitis outbreak resurfaced amid the coronavirus disease 2019 (COVID-19) pandemic in the Democratic Republic of Congo (DRC). The outbreak ...
Establishment of the African Medicines Agency: Progress, challenges and regulatory readiness
(Springer Nature, 2021)
Insufcient access to quality, safe, efcacious and afordable medical products in Africa has posed a signifcant challenge to public health for decades. In part, this is attributed to weak or absent policies and regulatory ...
Access to chronic medicines: patients’ preferences for a last kilometre medicine delivery service in Cape Town, South Africa
(Springer Nature, 2021)
: Chronic patients are required to access their chronic medicines on a regular basis, often only to refill
their repeat prescriptions. Adherence to chronic medicines is challenging and has stimulated health care providers
to ...
A pharmacist-led prospective antibiotic stewardship intervention improves compliance to community-acquired pneumonia guidelines in 39 public and private hospitals across South Africa
(Elsevier, 2020)
Introduction: Pharmacists in low-middle-income countries (LMIC) are few and lack antibiotic stewardship (AS) training. The ability was assessed of non-specialised pharmacists to implement stewardship interventions and ...
Exploring the utility of a spontaneous adverse drug reaction reporting system in identifying drug–drug interactions between antiretrovirals, antitubercular drugs, and cotrimoxazole: a case/non-case analysis
(Springer Nature, 2020)
Background: Drug–drug interactions (DDIs) cause significant morbidity and mortality, especially in patients with HIV with opportunistic infections such as tuberculosis. However, the literature on quantitative signal detection ...
Development of a method to determine the cost of breast cancer treatment with chemotherapy at Groote Schuur Hospital, Cape Town, South Africa
(SAMA, 2020)
There has been no comprehensive study determining the financial burden of breast cancer in the South African (SA) public sector. Objectives. To develop a method to determine the cost of breast cancer treatment with ...
A qualitative meta-synthesis of facilitators and barriers to tuberculosis diagnosis and treatment in Nigeria
(Springer Nature, 2021)
: Despite progress in tuberculosis (TB) control globally, TB continues to be a leading cause of death
from infectious diseases, claiming 1.2 million lives in 2018; 214,000 of these deaths were due to drug resistant
strains. ...
Evaluating pharmacy students’ knowledge and skills in reproductive, maternal, new-born and child health care at a South African university
(Springer Nature, 2021)
Maternal and child mortality is a global concern and one of South Africa’s quadruple burdens of
disease. As easily accessible frontline healthcare workers, pharmacists play an important role in the continuum of
maternal ...
Assessment of Vancomycin Pharmacokinetics and Dose Regimen Optimisation in Preterm Neonates
(Springer Nature, 2020)
The pharmacokinetics of vancomycin, a drug used for the treatment of methicillin-resistant Staphylococcus
aureus (MRSA), varies between paediatric and adult patients.
The objective of this study was to assess the ...