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Sub-analysis of cyp-guides data: Assessing the prevalence and impact of drug-gene interactions in an ethnically diverse cohort of depressed individuals
(Frontiers Media, 2022)
Minority groups are underrepresented in pharmacogenomics (PGx)
research. Recent sub-analysis of CYP-GUIDES showed reduced length of stay (LOS)
in depressed patients with CYP2D6 sub-functional status. Our primary objective ...
Comparative study on the topical and transdermal delivery of diclofenac incorporated in nano-emulsions, nano-emulgels, and a colloidal suspension
(Springer, 2022)
Transdermal delivery of active pharmaceutical ingredients (APIs) can be challenging, since the skin possesses a rate-limiting barrier, which may be overcome when APIs possess certain ideal physicochemical properties. The ...
Proprotein convertase subtilisin/kexin type 9 genetic screening using the vervet (Chlorocebus aethiops) model
(Journal of Medical Primatology, 2022)
Background: The proprotein convertase subtilisin/kexin type 9 (PCSK9) gene has come to prominence due to its reported function in the clearance of low-density li-poprotein cholesterol. The vervet monkey (Chlorocebus ...