Browsing Research Articles (Biotechnology) by Title
Now showing items 148-167 of 215
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Molecular adaptation mechanisms employed by ethanologenic bacteria in response to lignocellulose-derived inhibitory compounds
(Ivyspring, 2013)Current international interest in finding alternative sources of energy to the diminishing supplies of fossil fuels has encouraged research efforts in improving biofuel production technologies. In countries which lack ... -
Molecular application of aptamers in the diagnosis and treatment of cancer and communicable diseases
(MDPI, 2018)Cancer and infectious diseases such as Ebola, HIV, tuberculosis, Zika, hepatitis, measles and human schistosomiasis are serious global health hazards. The increasing annual morbidities and mortalities of these diseases ... -
Morpho-physiological, biochemical, and genetic responses to salinity in medicago truncatula
(MDPI, 2021)We used an integrated morpho-physiological, biochemical, and genetic approach to investigate the salt responses of four lines (TN1.11, TN6.18, JA17, and A10) of Medicago truncatula. Results showed that TN1.11 exhibited a ... -
Multifunctional Gold Nanoparticles for Improved Diagnostic and Therapeutic Applications: A Review
(Springer Open, 2021)The medical properties of metals have been explored for centuries in traditional medicine for the treatment of infections and diseases and still practiced to date. Platinum-based drugs are the first class of metal-based ... -
Nanotechnology-based delivery systems for antimicrobial peptides
(MDPI, 2021)Antimicrobial resistance (AMR) is a significant threat to global health. The conventional antibiotic pool has been depleted, forcing the investigation of novel and alternative antimicrobial strategies. Antimicrobial peptides ... -
Nanotechnology-based strategies for effective and rapid detection of sars-cov-2
(MDPI, 2021)The coronavirus disease 2019 (COVID-19) pandemic has gained worldwide attention and has prompted the development of innovative diagnostics, therapeutics, and vaccines to mitigate the pandemic. Diagnostic methods based ... -
Nanotechnology-based strategies for treatment of obesity, cancer and anti-microbial resistance: Highlights of the Department of Science and Innovation/mintek Nanotechnology Innovation centre biolabels research node at the University of the Western Cape
(MDPI, 2022)Nanotechnology has recently received much interest in various fields, including medicine. South Africa (SA) was the first country in Africa to adopt the technology with the aim of enhancing the national bio-economy and ... -
Nitric oxide (NO) regulates the expression of single-domain cystatins in glycine max (soybean)
(Southern Cross Publishing, 2013)Plant cystatins inhibit cysteine proteases and are important in regulating plant development and plant responses to biotic and abiotic stress. Furthermore, nitric oxide plays a signaling role in regulating plant responses ... -
Nitric oxide affects salt-induced changes in free amino acid levels in maize
(Elsevier, 2013)It was assumed that salt-induced redox changes affect amino acid metabolism in maize (Zea mays L.), and this influence may be modified by NO. The applied NaCl treatment reduced the fresh weight of shoots and roots. This ... -
Nodulation, leaf harvesting intensity and interval of the black-eyed bean (BEB) (Vigna unguiculata L. Walpers) cowpea type at the University of Zimbabwe, Harare, Zimbabwe
(Academic Journals, 2012)A glasshouse pot experiment was carried out at the University of Zimbabwe, Crop Science Department in 2006 to 2007 rainy season to determine the effect of leaf harvesting intensity and interval on cowpea biological nitrogen ... -
One-pot synthesis and characterization of InP/ZnSe semiconductor nanocrystals
(Elsevier, 2013)We report on the one-pot synthesis of InP/ZnSe quantum dots (QDs) using a precursor-based colloidal synthesis in a noncoordinating solvent environment. The structural and optical studies were carried out on the as-prepared ... -
Ozone and nitric oxide induce cGMP-dependent and independent transcription of defence genes in tobacco
(Wiley, 2009)Here, we analyse the temporal signatures of ozone (O3)-induced hydrogen peroxide (H2O2) and nitric oxide (NO) and the role of the second messenger guanosine 3′,5′-cyclic monophosphate (cGMP) in transcriptional changes ... -
Phenolic content, antioxidant, cytotoxic and antiproliferative effects of fractions of Vigna subterraenea (L.) verdc from Mpumalanga, South Africa
(Elsevier, 2021)Consistent intake of legumes has been correlated with decreased possibility of developing colorectal cancer (CRC) due to the content of some phytochemicals like polyphenols. Bambara groundnut (BGN) is an underutilized ... -
Piperonylic acid alters growth, mineral content accumulation and reactive oxygen species-scavenging capacity in chia seedlings
(Oxford University Press, 2022)p-Coumaric acid synthesis in plants involves the conversion of phenylalanine to trans-cinnamic acid via phenylalanine ammonia-lyase (PAL), which is then hydroxylated at the para-position under the action of trans-cinnamic ... -
Plant antimicrobial peptides (pamps): Features, applications, production, expression and challenges
(MDPI, 2022)The quest for an extraordinary array of defense strategies is imperative to reduce the challenges of microbial attacks on plants and animals. Plant antimicrobial peptides (PAMPs) are a subset of antimicrobial peptides ... -
Post-translational cleavage of recombinantly expressed nitrilase from Rhodococcus rhodochrous J1 yields a stable, active helical form
(Wiley, 2007)Nitrilases convert nitriles to the corresponding carboxylic acids and ammonia. The nitrilase from Rhodococcus rhodochrous J1 is known to be inactive as a dimer but to become active on oligomerization. The recombinant enzyme ... -
The potential of chalcone-capped gold nanoparticles for the management of diabetes mellitus
(Surfaces and Interfaces, 2021-08)Searching for new natural bioactive capping agents represent an urgent priority in the green synthesis of metal nanoparticles. Additionaly, the biosaftey of metal nanparticles is a major concern especially in medical ... -
PR-1-Like Protein as a Potential Target for the Identification of Fusarium oxysporum: An In Silico Approach
(BioTech, 2021-07)Fusarium oxysporum remains one of the leading causes of economic losses and poor crop yields; its detection is strained due to its presentation in various morphological and physiological forms. This research work sought ... -
Predicting haplogroups using a versatile machine learning program (PredYMaLe) on a new mutationally balanced 32 Y-STR multiplex (CombYplex): Unlocking the full potential of the human STR mutation rate spectrum to estimate forensic parameters
(Elsevier, 2020)We developed a new mutationally well-balanced 32 Y-STR multiplex (CombYplex) together with a machine learning (ML) program PredYMaLe to assess the impact of STR mutability on haplogourp prediction, while respecting forensic ... -
Prevalence of hypertension and its associated risk factors in a rural black population of Mthatha town,South Africa
(MPDI, 2021)The occurrence of hypertension has been increasing alarmingly in both low and middle-income countries. Despite acknowledging hypertension as the most common life-threatening risk factor for cardiovascular disease (CVD), a ...