Search
Now showing items 11-20 of 151
Cross-sectional study of the association of 5 single nucleotide polymorphisms with enalapril treatment response among South African adults with hypertension
(NLM (Medline), 2021-11-19)
This study investigates the association of 5 single nucleotide polymorphisms (SNPs) in selected genes (ABO, VEGFA, BDKRB2, NOS3, and ADRB2) with blood pressure (BP) response to enalapril. The study further assessed genetic ...
Predicting haplogroups using a versatile machine learning program (PredYMaLe) on a new mutationally balanced 32 Y-STR multiplex (CombYplex): Unlocking the full potential of the human STR mutation rate spectrum to estimate forensic parameters
(Elsevier, 2020)
We developed a new mutationally well-balanced 32 Y-STR multiplex (CombYplex) together with a machine learning (ML) program PredYMaLe to assess the impact of STR mutability on haplogourp prediction, while respecting forensic ...
Ethical publication of research on genetics and genomics of biological material: guidelines and recommendations
(Elsevier, 2020)
Forensic Science International: Genetics and Forensic Science International: Reports communicate research on a variety of biological materials using genetics and genomic methods. Numerous guidelines have been produced to ...
Three Novel Bacteria Associated with Two Centric Diatom Species from the Mediterranean Sea, Thalassiosira rotula and Skeletonema marinoi
(MDPI, 2021)
Diatoms are a successful group of microalgae at the base of the marine food web. For
hundreds of millions of years, they have shared common habitats with bacteria, which favored
the onset of interactions at different ...
MicroRNA-based regulation of Aurora A kinase in breast cancer
(Impact Journals, 2020)
The involvement of non-coding RNAs (ncRNAs) in cellular physiology and disease pathogenesis is becoming increasingly relevant in recent years specifically in cancer research. Breast cancer (BC) has become a health concern ...
DNA commission of the international society of forensic genetics (IGSF): recommendations on the interpretation of y-str results in forensic analysis
(Elsevier, 2020)
Forensic genetic laboratories perform a large amount of STR analyses of the Y chromosome, in particular to analyze the male part of complex DNA mixtures. However, the statistical interpretation of evidence retrieved from ...
Genetic characterisation of Campylobacter concisus: Strategies for improved genomospecies discrimination
(Elsevier, 2021)
Although at least two genetically distinct groups, or genomospecies, have been well documented for Campylobacter concisus, no phenotype has yet been identified for their differentiation and thus formal description as ...
Genetic association of solute carrier transporter gene variants with metformin response
(Balkan Journal of Medical Genetics, 2021)
Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterized by elevated blood glucose levels and is influenced by both genetic and environmental factors. It is treated with various classes of oral antidiabetic ...
Genomic association of single nucleotide polymorphisms with blood pressure response to hydrochlorothiazide among south african adults with hypertension
(MDPI, 2020)
: This study described single nucleotide polymorphisms (SNPs) in hydrochlorothiazideassociated genes and further assessed their correlation with blood pressure control among South
African adults living with hypertension. ...
Expression of cyclin-dependent kinases and their clinical significance with immune infiltrates could predict prognosis in colorectal cancer
(Elsevier, 2021)
Introduction: Colorectal cancer (CRC) is one of the most cancer-related mortalities worldwide and remains a major public health issue. Despite several attempts to develop promising therapies for CRC, its survival rate ...