Neuroprotective activities of Boophone haemanthoides (amaryllidaceae) extract and its chemical constituents
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Date
2020Author
Ibrakaw, Abobaker S.
Omoruyi, Sylvester I.
Ekpo, Okobi E.
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Parkinson’s disease (PD) is a neurodegenerative condition that progresses as age increases, and some of its major symptoms include tremor and postural and movement-related difficulties. To date, the treatment of PD remains a challenge because available drugs only treat the symptoms of the disease or possess serious side effects. In light of this, new treatment options are needed; hence, this study investigates the neuroprotective effects of an organic Boophone haemanthoides extract (BHE) and its bioactive compounds using an in vitro model of PD involving the toxin 1-methyl-4-phenylpyridinium (MPP+) and SH-SY5Y neuroblastoma cells.