Multistage antiplasmodial activity of hydroxyethylamine compounds,in vitroandin vivoevaluations
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Date
2020Author
Sharma, Neha R.
Gupta, Yash
Singh, Agam Prasad
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Malaria, a global threat to the human population, remains a challenge partly due to the fast-growing drug-resistant strains of Plasmodium species. New therapeutics acting against the pathogenic asexual and sexual stages, including liver-stage malarial infection, have now attained more attention in achieving malaria eradication efforts. In this paper, two previously identified potent antiplasmodial hydroxyethylamine (HEA) compounds were investigated for their activity against the malaria parasite's multiple life stages.