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Leptin deficiency, caused by malnutrition, makes you susceptible to sars-cov-2 infection but could offer protection from severe Covid-19
(American Society for Microbiology, 2021)
In much of the developing world, severe malnutrition is the most prevalent cause of immunodeficiency and affects up to 50% of the population in some
impoverished communities. As yet, we do not know how severe acute ...
Editorial commentary on draft of world health organization sixth edition laboratory manual for the examination and processing of human semen
(Korean Society for Sexual Medicine and Andrology, 2021)
Semen examination is the cornerstone of the evaluation of male fertility potential. Despite its apparent
simplicity, it is a complex series of assessments with
highly variable results that are subject to interpretation. ...
The new 6th edition of the WHO laboratory manual for the examination and processing of human semen: Is it a step toward better standard operating procedure?
(Shanghai Institute Materia Medica, 2021)
Semen analysis (SA) remains the
cornerstone of male infertility evaluation
and should ideally be performed by an
accredited andrology laboratory or in
vitro fertilization (IVF) clinics based on
the standards defined ...
Alkaloids: Therapeutic Potential against Human Coronaviruses
(MPDI, 2020)
Alkaloids are a class of natural products known to have wide pharmacological activity and have great potential for the development of new drugs to treat a wide array of pathologies. Some alkaloids have antiviral activity ...
Causes and consequences of sperm mitochondrial dysfunction
(Wiley-Blackwell, 2020)
Mitochondria have multiple functions, including synthesis of adenine triphosphate,
production of reactive oxygen species, calcium signalling, thermogenesis and apoptosis. Mitochondria have a significant contribution in ...
Ethnopharmacology, therapeutic properties and nutritional potentials of Carpobrotus edulis: A comprehensive review
(MPDI, 2020)
Carpobrotus edulis, formerly known as Mesembryanthemum edule L, belongs to the Aizoaceae
family of plants. It is a facultative halophytic invasive medicinal and edible succulent plant that is
native to South Africa and ...
Tyrosinase and melanogenesis inhibition by indigenous African plants: A review
(Multidisciplinary Digital Publishing Institute (MDPI), 2020)
The indiscriminate use of non-regulated skin lighteners among African populations has raised health concerns due to the negative effects associated with skin lightener toxicity. For this reason, there is a growing interest ...
Reactive oxygen species in male reproduction: A boon or a bane?
(Wiley, 2020)
Reactive oxygen species (ROS) are free radicals derived from oxygen during normal cellular metabolism. ROS play a crucial role in the physiological processes and signalling pathways associated with male fertility. At ...
Total antioxidant capacity—Relevance, methods and clinical implications
(Blackwell Publishing Ltd, 2020)
Oxidative stress is pre‐empted by an adequate level of antioxidants, which scavenge oxidants when they are produced in excess by different sources, including leukocytes and immature spermatozoa. Enzymatic antioxidants, ...
Ritalinic acid stimulates human sperm motility and maintains vitality in vitro
(Korean Society for Sexual Medicine and Andrology, 2020)
To evaluate the in vitro impact of ritalinic acid (RA), a major metabolite of methylphenidate (drug to treat attention-deficit hyperactivity disorder), on sperm motility, vitality and oxidative stress. Materials and Methods: ...