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Now showing items 11-19 of 19
Causes and consequences of sperm mitochondrial dysfunction
(Wiley-Blackwell, 2020)
Mitochondria have multiple functions, including synthesis of adenine triphosphate,
production of reactive oxygen species, calcium signalling, thermogenesis and apoptosis. Mitochondria have a significant contribution in ...
Reactive oxygen species in male reproduction: A boon or a bane?
(Wiley, 2020)
Reactive oxygen species (ROS) are free radicals derived from oxygen during normal cellular metabolism. ROS play a crucial role in the physiological processes and signalling pathways associated with male fertility. At ...
Total antioxidant capacity—Relevance, methods and clinical implications
(Blackwell Publishing Ltd, 2020)
Oxidative stress is pre‐empted by an adequate level of antioxidants, which scavenge oxidants when they are produced in excess by different sources, including leukocytes and immature spermatozoa. Enzymatic antioxidants, ...
Ritalinic acid stimulates human sperm motility and maintains vitality in vitro
(Korean Society for Sexual Medicine and Andrology, 2020)
To evaluate the in vitro impact of ritalinic acid (RA), a major metabolite of methylphenidate (drug to treat attention-deficit hyperactivity disorder), on sperm motility, vitality and oxidative stress. Materials and Methods: ...
Utility of Antioxidants in the Treatment of Male Infertility: Clinical Guidelines Based on a Systematic Review and Analysis of Evidence
(The world journal of men's health, 2021)
It is widely accepted that oxidative stress plays an important role in the pathophysiology of male infertility and that antioxidants
could have a significant role in the treatment of male infertility. The main objectives ...
The sixth edition of the WHO manual for human semen analysis: A critical review and SWOT analysis
(MDPI, 2021)
Semen analysis is the cornerstone of male fertility evaluation with WHO guidelines
providing the basis for procedural standardization and reference values worldwide. The first WHO
manual was published in 1980, and five ...
Differential sensitivity of two endothelial cell lines to hydrogen peroxide toxicity: Relevance for in vitro studies of the blood–brain barrier
(MPDI, 2020)
Oxidative stress (OS) has been linked to blood–brain barrier (BBB) dysfunction which in
turn has been implicated in the initiation and propagation of some neurological diseases. In this study,
we profiled, for the first ...
Oxidative stress and assisted reproduction: A comprehensive review of its pathophysiological role and strategies for optimizing embryo culture environment
(MDPI, 2022)
Oxidative stress (OS) due to an imbalance between reactive oxygen species (ROS) and
antioxidants has been established as an important factor that can negatively affect the outcomes
of assisted reproductive techniques ...
Overview of the effects of moringa oleifera leaf extract on oxidative stress and male infertility: a review
(MDPI, 2023)
According to a recent report by the WHO, 50–80 million people suffer with infertility. Amongst these populations, male counterparts account for 20–50% of infertility cases. The aetiology of infertility in men includes many ...