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The effect of sperm DNA fragmentation on intracytoplasmic sperm injection outcome
(Wiley, 2021)
Our study objective was to assess the effect of various sperm DNA fragmentation
levels on clinical intracytoplasmic sperm injection outcome. This retrospective study
included 392 patients who underwent ICSI and performed ...
Relevance of leukocytospermia and semen culture and its true place in diagnosing and treating male infertility
(Korean Society for Sexual Medicine and Andrology, 2021)
The current WHO 2010 manual for human semen analysis defines leukocytospermia as the presence of peroxidase-positive
leukocytes at a concentration >1×106
/mL of semen. Granular leukocytes when activated are capable of ...
Sperm morphology assessment in the era of intracytoplasmic sperm injection: Reliable results require focus on standardization, quality control, and training
(Korean Society for Sexual Medicine and Andrology, 2021)
Semen analysis is the first, and frequently, the only step in the evaluation of male fertility. Although the laboratory procedures
are conducted according to the World Health Organization (WHO) guidelines, semen analysis ...
Etiologies of sperm DNA damage and its impact on male infertility
(Blackwell Publishing Ltd, 2021)
Male factor is responsible for up to 50% of infertility cases in the world. Semen analysis is considered the cornerstone of laboratory evaluation of male infertility, but it has its own drawbacks and fails to predict the ...
Semiquantitative promoter methylation of MLH1 and MSH2 genes and their impact on sperm DNA fragmentation and chromatin condensation in infertile men
(Blackwell Publishing Ltd, 2021)
To investigate the semiquantitative methylation alterations of MLH1 and MSH2 and the possible association among methylation of MLH1 and MSH2, sperm DNA fragmentation and sperm chromatin condensation in idiopathic ...
Response to letter to the Editor: The therapeutic strategy of drug re-positioning to induce autophagic cell death in brain malignancy
(Springer Nature, 2021)
We thank Dr Yoshida for his valuable comments and interest in our study which describes the anti-cancer activity
of DS00329, a novel derivative of the anti-psychotic drug
phenothiazine, in glioblastoma multiforme (GBM) ...
Corrigendum: Immunological changes during space travel: A ground-based evaluation of the impact of neutron dose rate on plasma cytokine levels in human whole blood cultures
(Frontiers Media, 2021)
A better understanding of the combined impact of different space stressors on
human health is urgently warranted, considering the upcoming long-duration missions
beyond lower Earth orbit. Therefore, a growing number of ...
Leptin deficiency, caused by malnutrition, makes you susceptible to sars-cov-2 infection but could offer protection from severe Covid-19
(American Society for Microbiology, 2021)
In much of the developing world, severe malnutrition is the most prevalent cause of immunodeficiency and affects up to 50% of the population in some
impoverished communities. As yet, we do not know how severe acute ...
Editorial commentary on draft of world health organization sixth edition laboratory manual for the examination and processing of human semen
(Korean Society for Sexual Medicine and Andrology, 2021)
Semen examination is the cornerstone of the evaluation of male fertility potential. Despite its apparent
simplicity, it is a complex series of assessments with
highly variable results that are subject to interpretation. ...
The new 6th edition of the WHO laboratory manual for the examination and processing of human semen: Is it a step toward better standard operating procedure?
(Shanghai Institute Materia Medica, 2021)
Semen analysis (SA) remains the
cornerstone of male infertility evaluation
and should ideally be performed by an
accredited andrology laboratory or in
vitro fertilization (IVF) clinics based on
the standards defined ...