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Alkaloids: Therapeutic Potential against Human Coronaviruses
(MPDI, 2020)
Alkaloids are a class of natural products known to have wide pharmacological activity and have great potential for the development of new drugs to treat a wide array of pathologies. Some alkaloids have antiviral activity ...
Causes and consequences of sperm mitochondrial dysfunction
(Wiley-Blackwell, 2020)
Mitochondria have multiple functions, including synthesis of adenine triphosphate,
production of reactive oxygen species, calcium signalling, thermogenesis and apoptosis. Mitochondria have a significant contribution in ...
Ethnopharmacology, therapeutic properties and nutritional potentials of Carpobrotus edulis: A comprehensive review
(MPDI, 2020)
Carpobrotus edulis, formerly known as Mesembryanthemum edule L, belongs to the Aizoaceae
family of plants. It is a facultative halophytic invasive medicinal and edible succulent plant that is
native to South Africa and ...
Tyrosinase and melanogenesis inhibition by indigenous African plants: A review
(Multidisciplinary Digital Publishing Institute (MDPI), 2020)
The indiscriminate use of non-regulated skin lighteners among African populations has raised health concerns due to the negative effects associated with skin lightener toxicity. For this reason, there is a growing interest ...
Reactive oxygen species in male reproduction: A boon or a bane?
(Wiley, 2020)
Reactive oxygen species (ROS) are free radicals derived from oxygen during normal cellular metabolism. ROS play a crucial role in the physiological processes and signalling pathways associated with male fertility. At ...
Total antioxidant capacity—Relevance, methods and clinical implications
(Blackwell Publishing Ltd, 2020)
Oxidative stress is pre‐empted by an adequate level of antioxidants, which scavenge oxidants when they are produced in excess by different sources, including leukocytes and immature spermatozoa. Enzymatic antioxidants, ...
Ritalinic acid stimulates human sperm motility and maintains vitality in vitro
(Korean Society for Sexual Medicine and Andrology, 2020)
To evaluate the in vitro impact of ritalinic acid (RA), a major metabolite of methylphenidate (drug to treat attention-deficit hyperactivity disorder), on sperm motility, vitality and oxidative stress. Materials and Methods: ...
The beneficial role of anchomanes difformis in stz-induced reproductive dysfunction in male wistar rats
(Dove Medical Press, 2020)
Progression of diabetes mellitus has increasingly led to several diabetic complications. Diabetes is one of the major factors implicated in male reproductive system damage. Recent approaches such as the use of medicinal ...
Green tea consumption increases sperm concentration and viability in male rats and is safe for reproductive, liver and kidney health
(Springer Nature, 2020)
Green tea is a popularly consumed beverage worldwide and contains polyphenols, whose antioxidant activities could improve sperm parameters and fertility thereof. We investigated the effect of green tea on the male rat ...
Immunological changes during space travel: A ground-based evaluation of the impact of Neutron Dose Rate on Plasma Cytokine levels in human whole blood cultures
(Frontiers Media S.A., 2020)
A better understanding of the combined impact of different space stressors on
human health is urgently warranted, considering the upcoming long-duration missions
beyond lower Earth orbit. Therefore, a growing number of ...