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Total antioxidant capacity—Relevance, methods and clinical implications
(Blackwell Publishing Ltd, 2021)
Oxidative stress is pre-empted by an adequate level of antioxidants, which scavenge oxidants when they are produced in excess by different sources, including leukocytes and immature spermatozoa. Enzymatic antioxidants, ...
High-resolution insights into the in vitro developing blood-brain barrier: Novel morphological features of endothelial nanotube function
(Frontiers Media, 2021)
High-resolution electron microscopy (HREM) imaging of the in vitro blood-brain barrier
(BBB), is a promising modality for investigating the dynamic morphological interplay
underpinning BBB development. The successful ...
A scientometric analysis of research publications on male infertility and assisted reproductive technology
(Blackwell Publishing Ltd, 2021)
Assisted reproductive technologies (ART) are considered as one of the primary management options to address severe male factor infertility. The purpose of this study was to identify the research trends in the field of male ...
The effect of sperm DNA fragmentation on intracytoplasmic sperm injection outcome
(Wiley, 2021)
Our study objective was to assess the effect of various sperm DNA fragmentation
levels on clinical intracytoplasmic sperm injection outcome. This retrospective study
included 392 patients who underwent ICSI and performed ...
Relevance of leukocytospermia and semen culture and its true place in diagnosing and treating male infertility
(Korean Society for Sexual Medicine and Andrology, 2021)
The current WHO 2010 manual for human semen analysis defines leukocytospermia as the presence of peroxidase-positive
leukocytes at a concentration >1×106
/mL of semen. Granular leukocytes when activated are capable of ...
Sperm morphology assessment in the era of intracytoplasmic sperm injection: Reliable results require focus on standardization, quality control, and training
(Korean Society for Sexual Medicine and Andrology, 2021)
Semen analysis is the first, and frequently, the only step in the evaluation of male fertility. Although the laboratory procedures
are conducted according to the World Health Organization (WHO) guidelines, semen analysis ...
Etiologies of sperm DNA damage and its impact on male infertility
(Blackwell Publishing Ltd, 2021)
Male factor is responsible for up to 50% of infertility cases in the world. Semen analysis is considered the cornerstone of laboratory evaluation of male infertility, but it has its own drawbacks and fails to predict the ...
Semiquantitative promoter methylation of MLH1 and MSH2 genes and their impact on sperm DNA fragmentation and chromatin condensation in infertile men
(Blackwell Publishing Ltd, 2021)
To investigate the semiquantitative methylation alterations of MLH1 and MSH2 and the possible association among methylation of MLH1 and MSH2, sperm DNA fragmentation and sperm chromatin condensation in idiopathic ...
Response to letter to the Editor: The therapeutic strategy of drug re-positioning to induce autophagic cell death in brain malignancy
(Springer Nature, 2021)
We thank Dr Yoshida for his valuable comments and interest in our study which describes the anti-cancer activity
of DS00329, a novel derivative of the anti-psychotic drug
phenothiazine, in glioblastoma multiforme (GBM) ...
Corrigendum: Immunological changes during space travel: A ground-based evaluation of the impact of neutron dose rate on plasma cytokine levels in human whole blood cultures
(Frontiers Media, 2021)
A better understanding of the combined impact of different space stressors on
human health is urgently warranted, considering the upcoming long-duration missions
beyond lower Earth orbit. Therefore, a growing number of ...