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Cytotoxic and cell cycle arrest properties of two steroidal alkaloids isolated from Holarrhena floribunda (G. Don) T. Durand & Schinz leaves
(BMC, 2019)
The plant Holarrhena floribunda (H. floribunda; G. Don) is indigenous to sub-Saharan Africa and is traditionally used to treat several ailments. The present study was carried out to isolate and characterize bioactive ...
Real-time assessment of interspecies candida biofilm formation
(Bentham Open, 2022-12-30)
Background:
Candida infections are responsible for increased morbidity and mortality in immunocompromised patients, with Candida having the ability to form highly structured biofilms that protect them from the external ...
Preservation of shortening velocity and power output in single muscle fibres from patients with idiopathic inflammatory myopathies
(Springer, 2022)
Idiopathic inflammatory myopathies (IIMs) are autoimmune disorders of skeletal muscle causing weakness and disability.
Utilizing single fibre contractility studies, we have previously shown that contractility is affected ...
Face-to-face versus online-based lectures: A COVID-19 induced study on assessments
(Frontiers in Education, 2022)
The students were found to be resilient in adapting to things
and learning, online presentations, and computer-based assessments. No
gender-based difference or advantage to adjusting to newly introduced
blended learning ...
Call for special issue papers: Global public health — contributions of traditional, complementary, and integrative medicine in primary care
(Mary Ann Liebert, 2022)
The 2018 Declaration of Astana* issued by the World Health Organization (WHO) and the United Nations Children’s Fund (UNICEF) represents a
landmark step for all of primary health care, public health, and traditional
co ...
The IPDGC/GP2 Hackathon - an open science event for training in data science, genomics, and collaboration using Parkinson’s disease data
(Nature Research, 2023)
Open science and collaboration are necessary to facilitate the advancement of Parkinson’s disease (PD) research. Hackathons are collaborative events that bring together people with different skill sets and backgrounds to ...
Potential for increasing folate contents of traditional African fermented sorghum gruel (Motoho) using presumptive probiotic lactic acid bacteria
(Elsevier, 2023)
Folate deficiency is commonly observed in most developing countries. Lactic acid bacteria (LAB) fermentation of
cereal-based foods could be an alternative to improving folate intake. This study evaluated the possibility ...
Muscle fiber type and metabolic profiles of four muscles from the African black ostrich
(Meat Science, 2023)
Muscle fiber type, fiber cross-sectional area (CSA), enzyme activities (citrate synthase (CS), 3-hydroxyacetyl Co A dehydrogenase (3HAD), lactate dehydrogenase (LDH) and phosphofructokinase (PFK)) and glycogen content were ...
Use of a rat ex-vivo testis culture method to assess toxicity of select known male reproductive toxicants
(Elsevier, 2016)
Due to the complex physiology of the testes, in vitro models have been largely unsuccessful at modeling testicular toxicity in vivo. We conducted a pilot study to evaluate the utility of the Durand ex vivo rat seminiferous ...
Unveiling the Inhibitory Potentials of Peptidomimetic Azanitriles and Pyridyl Esters towards SARS-CoV-2Main Protease: A MolecularModelling Investigation
(MDPI, 2023)
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for
COVID-19, which was declared a global pandemic in March 2020 by the World Health Organization
(WHO). Since SARS-CoV-2 main protease plays ...