| dc.contributor.author | Masilela, Charity | |
| dc.contributor.author | Adeniyi, Oladele Vincent | |
| dc.contributor.author | Benjeddou, Mongi | |
| dc.date.accessioned | 2022-09-06T09:41:43Z | |
| dc.date.available | 2022-09-06T09:41:43Z | |
| dc.date.issued | 2022 | |
| dc.identifier.citation | Masilela, C. et al. (2022). Single nucleotide polymorphisms in amlodipine-associated genes and their correlation with blood pressure control among South African adults with hypertension. Genes, 13(8), 1394. https://doi.org/10.3390/genes13081394 | en_US |
| dc.identifier.issn | 2073-4425 | |
| dc.identifier.uri | https://doi.org/10.3390/genes13081394 | |
| dc.identifier.uri | http://hdl.handle.net/10566/7813 | |
| dc.description.abstract | This study describes the single nucleotide polymorphisms (SNPs) in amlodipineassociated
genes and assesses their correlation with blood pressure control among South African
adults with hypertension. Methods: In total, 304 hypertensive patients on amlodipine treatment
belonging to the indigenous Swati, Xhosa and Zulu population groups of South Africa were recruited
between June 2017 and June 2019. Participants were categorized into: controlled (blood
pressure < 140/90 mmHg) and uncontrolled (blood pressure 140/90 mmHg) hypertension. Thirteen
SNPs in amlodipine pharmacogenes with a high PharmGKB evidence base were selected and
genotyped using MassArray (Agena BioscienceTM). | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | MDPI | en_US |
| dc.subject | Amlodipine | en_US |
| dc.subject | Nucleotide polymorphisms | en_US |
| dc.subject | Blood pressure | en_US |
| dc.subject | Hypertension | en_US |
| dc.subject | South Africa | en_US |
| dc.title | Single nucleotide polymorphisms in amlodipine-associated genes and their correlation with blood pressure control among South African adults with hypertension | en_US |
| dc.type | Article | en_US |
