| dc.contributor.author | Obikeze, Kenechukwu | |
| dc.contributor.author | Gainsford, Garth | |
| dc.contributor.author | Kamaar, Maajidah | |
| dc.date.accessioned | 2022-09-21T09:24:24Z | |
| dc.date.available | 2022-09-21T09:24:24Z | |
| dc.date.issued | 2022 | |
| dc.identifier.citation | Obikeze, K. et al. (2022). Crataegus monogyna and centella asiatica extracts as inhibitors of cathepsin s. Advances in Pharmacology and Pharmacy, 10(4), 247-252. 10.13189/app.2022.100403 | en_US |
| dc.identifier.issn | 2332-0044 | |
| dc.identifier.uri | 10.13189/app.2022.100403 | |
| dc.identifier.uri | http://hdl.handle.net/10566/7938 | |
| dc.description.abstract | Cathepsin cysteine proteases such as
cathepsin S are responsible for the unfavorable and
irreversible dysregulation of extracellular matrix (ECM)
proteolysis found in cardiomyopathy, heart valve diseases
and atherosclerosis. Cathepsin S plays a central role in
ECM remodeling, which has been implicated in the
development and progression of cardiovascular diseases.
The current study aimed to evaluate the aqueous and
ethanol extracts of the berries of Crataegus monogyna and
the leaves of Centella asiatica for inhibition of cathepsin S
activity using an in vitro fluorescent assay. | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | Horizon Research Publishing | en_US |
| dc.subject | Crataegus monogyna | en_US |
| dc.subject | Cathepsin S | en_US |
| dc.subject | Cardiovascular disease | en_US |
| dc.subject | Centella asiatica | en_US |
| dc.subject | Pharmacology | en_US |
| dc.title | Crataegus monogyna and centella asiatica extracts as inhibitors of cathepsin s | en_US |
| dc.type | Article | en_US |
