Browsing by Author "Hadebe, Sabelo"
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Deletion of IL-4Rα signalling on B cells limits hyperresponsiveness depending on antigen-load.
Hadebe, Sabelo; Khumalo, Jermaine; Mangali, Sandisiwe; Mthembu, Nontobeko; Ndlovu, Hlumani; Scibiorek, Martyna; Ngomti, Amkele; Brombacher, Frank (Elsevier, 2020)B cells play an important role in allergies through secretion of IgE. Interleukin 4 50 receptor α (IL-4Rα) is key in allergic asthma and regulates type 2 cytokine production, IgE 51 secretion and airway hyperresponsiveness ...