Browsing Faculty of Natural Sciences by Author "Ekpo, Okobi Eko"
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Comparative study of the antioxidant constituents, activities and the gc-ms quantification and identification of fatty acids of four selected helichrysum species
Akinyede, Kolajo Adedamola; Hughes, Gail Denise; Ekpo, Okobi Eko (MDPI, 2022)Helichrysum Mill. (Asteraceae) is a plant genus comprising distinctively of aromatic plants of about 500–600 species. Since most of these plants have not been previously studied, extensive profiling helps to validate ... -
Cytotoxic and cell cycle arrest properties of two steroidal alkaloids isolated from Holarrhena floribunda (G. Don) T. Durand & Schinz leaves
Badmus, Jelili Abiodun; Ekpo, Okobi Eko; Hussein, A. A. (BMC, 2019)The plant Holarrhena floribunda (H. floribunda; G. Don) is indigenous to sub-Saharan Africa and is traditionally used to treat several ailments. The present study was carried out to isolate and characterize bioactive ... -
Ethnopharmacology, therapeutic properties and nutritional potentials of Carpobrotus edulis: A comprehensive review
Akinyede, Kolajo Adedamola; Ekpo, Okobi Eko (MPDI, 2020)Carpobrotus edulis, formerly known as Mesembryanthemum edule L, belongs to the Aizoaceae family of plants. It is a facultative halophytic invasive medicinal and edible succulent plant that is native to South Africa and ... -
In vitro evaluation of the anti-diabetic potential of aqueous acetone Helichrysum petiolare extract (AAHPE) with molecular docking relevance in diabetes mellitus
Akinyede, Kolajo Adedamola; Oyewusi, Habeebat Adekilekun; Hughes, Gail Denise; Ekpo, Okobi Eko (MDPI, 2021-12)Diabetes mellitus (DM) is a chronic metabolic condition that can lead to significant complications and a high fatality rate worldwide. Efforts are ramping up to find and develop novel α-glucosidase and α-amylase inhibitors ... -
In vitro evaluation of the antiproliferative activity of Carpobrotus edulis on human neuroblastoma cells
Ekpo, Okobi Eko; Enogieru, Adaze Bijou; Omoruyi, Sylvester Ifeanyi (Elsivier, 2021)Neuroblastoma is a solid neuroendocrine tumour located outside the cranial cavity and contributes about 15% of all cancer‑associated deaths in children. Treatment of neuroblastoma is quite challenging and involves the use ... -
Rutin as a potent antioxidant: implications for neurodegenerative disorders
Enogieru, Adaze Bijou; Haylett, William; Hiss, Donavon Charles; Bardien, Soraya; Ekpo, Okobi Eko (Hindawi Publishing Corporation, 2018)A wide range of neurodegenerative diseases (NDs), including Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, and prion diseases, share common mechanisms such as neuronal loss, apoptosis, mitochondrial ...