Browsing Faculty of Natural Sciences by Subject "Reactive oxygen species"
Now showing items 1-19 of 19
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Antioxidant and apoptosis-inhibition potential of Carpobrotus edulis in a model of parkinson’s disease
(African Association of Physiological Sciences, 2018)Background: Parkinson’s disease (PD) is a neurological disorder resulting from the progressive loss of dopaminergic neurons. There is currently no known cure for PD, thus the search for complementary and alternative medicines ... -
Antioxidant responses are associated with differences in drought tolerance between maize and sorghum
(Arid land institute, 2021)Drought is a major cause of decreased yield in crops worldwide. Sorghum (Sorghum bicolor) and maize (Zea mays) are two of the key crops in Africa serving as human food as well as livestock feed. For improved crop ... -
Aqueous leaf extract of Moringa oleifera reduced intracellular ROS production, DNA fragmentation and acrosome reaction in Human spermatozoa in vitro
(Blackwell Publishing Ltd, 2021)The effects of aqueous leaf extract of Moringa oleifera (MO) on human sperm functions and integrity was studied in vitro. Semen was obtained by masturbation after 3–5 days' abstinence from 34 healthy donors in Western Cape, ... -
Aqueous leaf extract of Sutherlandia frutescens attenuates ROS-induced apoptosis and loss of mitochondrial membrane potential in MPP+-treated SH-SY5Y cells
(University of Benin, 2020)To investigate the neuroprotective activity of the aqueous extract of Sutherlandia frutescens (SF) against 1-methyl-4-phenylpyridinium (MPP+)-induced toxicity in SH-SY5Y neuroblastoma cells. Methods: SH-SY5Y neuroblastoma ... -
Effect of Cissampelos capensis rhizome extract on human spermatozoa in vitro
(Wiley, 2014)Cissampelos capensis is commonly known by the Afrikaans name ‘dawidjies’ or ‘dawidjieswortel’. C. capensis is the most important and best-known medicinal plant of the family Menispermaceae used by the Khoisan and other ... -
Exogenous 3,3′-diindolylmethane improves vanadium stress tolerance in brassica napus seedling shoots by modulating antioxidant enzyme activities
(MDPI, 2021)3,3′-diindolylmethane (DIM) belongs to a family of indole glucosinolate compounds that have been shown to improve Brassica napus growth through the modulation of reactive oxygen species when applied exogenously. The B. ... -
In vitro effects of aqueous extract of unfermented rooibos on human spermatozoa
(Wiley, 2022)The inability to conceive is a baleful experience for thousands of couples worldwide. Among different well-known reproductive techniques, medicinal plants have been utilized to treat male infertility. Medicinal plants, ... -
In vitro evaluation of the antiproliferative activity of Carpobrotus edulis on human neuroblastoma cells
(Elsivier, 2021)Neuroblastoma is a solid neuroendocrine tumour located outside the cranial cavity and contributes about 15% of all cancer‑associated deaths in children. Treatment of neuroblastoma is quite challenging and involves the use ... -
In vitro neuroprotective effects of boophone disticha, brunsvigia bosmaniae and strumaria truncata extracts in SH-SY5Y cells
(Elsevier B.V., 2024)Parkinson's disease (PD) is the second most common neurodegenerative disorder after Alzheimer's disease. The pathological hallmarks of PD are defined by the loss of dopaminergic neurons in the substantia nigra pars compacta ... -
Male infertility, oxidative stress and antioxidants
(IntechOpen, 2021)Within the male reproductive system, oxidative stress (OS) has been identified as prevailing etiology of male infertility. The effects of reactive oxygen species (ROS) on male fertility depend on the dimensions, “modus ... -
Overview of the effects of moringa oleifera leaf extract on oxidative stress and male infertility: a review
(MDPI, 2023)According to a recent report by the WHO, 50–80 million people suffer with infertility. Amongst these populations, male counterparts account for 20–50% of infertility cases. The aetiology of infertility in men includes many ... -
Reactive oxygen species and male reproductive hormones
(BMC, 2018)Reports of the increasing incidence of male infertility paired with decreasing semen quality have triggered studies on the effects of lifestyle and environmental factors on the male reproductive potential. There are ... -
Reactive oxygen species and male reproductive hormones
(BMC, 2018)Reports of the increasing incidence of male infertility paired with decreasing semen quality have triggered studies on the effects of lifestyle and environmental factors on the male reproductive potential. There are ... -
Reactive oxygen species in male reproduction: A boon or a bane?
(Blackwell Publishing Ltd, 2021)Reactive oxygen species (ROS) are free radicals derived from oxygen during normal cellular metabolism. ROS play a crucial role in the physiological processes and signalling pathways associated with male fertility. At ... -
The role of infections and leukocytes in male infertility
(Blackwell Publishing Ltd, 2021)Declining birth rates are one of the problems facing society today. Male counterparts are responsible for about half of the infertility cases, and genitourinary tract infections may play a contributing role in approximately ... -
Role of oxidative stress in male infertility
(Bioscientifica Ltd, 2023)Infertility affects millions of couples worldwide. Oxidative stress (OS) causes peroxidation of lipids and damage to spermatozoa, thus, reducing the quality of seminal parameters. In addition, the differences in the levels ... -
Total antioxidant capacity—Relevance, methods and clinical implications
(Blackwell Publishing Ltd, 2021)Oxidative stress is pre-empted by an adequate level of antioxidants, which scavenge oxidants when they are produced in excess by different sources, including leukocytes and immature spermatozoa. Enzymatic antioxidants, ... -
Total antioxidant capacity—Relevance, methods and clinical implications
(Blackwell Publishing Ltd, 2020)Oxidative stress is pre‐empted by an adequate level of antioxidants, which scavenge oxidants when they are produced in excess by different sources, including leukocytes and immature spermatozoa. Enzymatic antioxidants, ... -
An update on the techniques used to measure oxidative stress in seminal plasma
(Blackwell Publishing Ltd, 2021)Reactive oxygen species (ROS) are produced in significant amounts by spermatozoa and leucocytes. They are necessary to carry out various physiological functions such as sperm capacitation, hyperactivation, acrosome reaction, ...