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HIV-1 diversity and the implementation of integrase strand-transfer inhibitors as part of combination antiretroviral therapy
(SAMA, 2020)
: The integrase (IN) strand-transfer inhibitor (InSTI)
dolutegravir (DTG) is now recommended by the World Health
Organization as part of salvage and/or first-line combination
antiretroviral therapy (cART).[1] DTG has a ...
Analyses of HIV-1 integrase sequences prior to South African national HIV-treatment program and available of integrase inhibitors in Cape Town, South Africa
(Nature Publishing Group, 2018)
HIV-Integrase (IN) has proven to be a viable target for highly specific HIV-1 therapy. We aimed to
characterize the HIV-1 IN gene in a South African context and identify resistance-associated mutations
(RAMs) against ...