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Computational applications in secondary metabolite discovery (caismd): An online workshop
(BMC, 2021)
We report the major conclusions of the online open-access workshop “Computational Applications in Secondary
Metabolite Discovery (CAiSMD)” that took place from 08 to 10 March 2021. Invited speakers from academia and
industry ...
Protein profiling in unlocking the basis of varicocele-associated infertility
(Blackwell Publishing Ltd, 2021)
Varicocele is one of the major causes of male infertility and has a negative impact on spermatogenesis. The conventional semen analysis does not reveal the underlying subcellular mechanisms associated with defects in ...
Proteomic identification and meta-analysis in salvia hispanica RNA-seq de novo assemblies
(2021)
While proteomics has demonstrated its value for model organisms and for organisms with mature genome sequence annotations, proteomics has been of less value in nonmodel organisms that are unaccompanied by genome sequence ...
Using a multiple-delivery-mode training approach to develop local capacity and infrastructure for advanced bioinformatics in Africa
(Public Library of Science, 2021)
With more microbiome studies being conducted by African-based research groups, there is an increasing demand for knowledge and skills in the design and analysis of microbiome studies and data. However, high-quality ...
Transcriptomics of the Rooibos (Aspalathus linearis) Species Complex
(MDPI, 2020)
Rooibos (Aspalathus linearis), widely known as a herbal tea, is endemic to the Cape Floristic Region of South Africa (SA). It produces a wide range of phenolic compounds that have been associated with diverse health-promoting ...
Capacity building for whole genome sequencing of Mycobacterium tuberculosis and bioinformatics in high TB burden countries
(Oxford University Press, 2020)
Background
Whole-genome sequencing (WGS) is increasingly used for Mycobacterium tuberculosis (Mtb) research. Countries with the highest tuberculosis (TB) burden face important challenges to integrate WGS into surveillance ...
Diagnostic approaches of pneumonia for commercial-scale biomedical applications: An overview
(Taylor & Francis, 2020)
Pneumonia remains the leading infectious cause of death among children under five years of age,
and the elderly. Several biomarkers, which have been identified for its diagnosis lack specificity, as
they could not ...
Ten simple rules for developing bioinformatics capacity at an academic institution
(Public Library of Science, 2021)
Bioinformatics is an applied interdisciplinary field whose primary purpose is to develop and
deploy computational techniques to store, organize, and aid in the analysis and interpretation
of large-scale data obtained ...
Three novel bacteria associated with two centric diatom species from the Mediterranean Sea, Thalassiosira rotula and Skeletonema marinoi
(MPDI, 2021)
Diatoms are a successful group of microalgae at the base of the marine food web. For
hundreds of millions of years, they have shared common habitats with bacteria, which favored
the onset of interactions at different ...
Exploring new genetic variants within col5a1 intron 4‐exon 5 region and tgf‐β family with risk of anterior cruciate ligament ruptures
(Wiley, 2020)
Variants within genes encoding structural and regulatory elements of ligaments have
been associated with musculoskeletal soft tissue injury risk. The role of intron 4‐exon
5 variants within the α1 chain of type V collagen ...