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The Coronavirus Nucleocapsid is a Multifunctional Protein
(MDPI, 2014)
The coronavirus nucleocapsid (N) is a structural protein that forms complexes with genomic RNA, interacts with the viral membrane protein during virion assembly and plays a critical role in enhancing the efficiency of virus ...
Molecular detection of tick-borne pathogen diversities in ticks from livestock and reptiles along the shores and adjacent islands of lake Victoria and lake Baringo, Kenya
(Frontiers Media, 2017)
Tick-borne pathogens (TBPs) are responsible for some of the
most serious emerging infectious diseases facing sub-Saharan
Africa (SSA) and the rest of the world today (1, 2). In Kenya,
TBPs (including viral diseases—arboviruses) ...
Potential broad spectrum inhibitors of the coronavirus 3CLpro: A virtual screening and structure-based drug design study
(MDPI, 2015)
Human coronaviruses represent a significant disease burden; however, there is currently no antiviral strategy to combat infection. The outbreak of severe acute respiratory syndrome (SARS) in 2003 and Middle East respiratory ...
Characterisation of human coronavirus-NL63 nucleocapsid protein
(Academic Journals, 2012)
Coronavirus N is a multifunctional protein that plays an essential role in enhancing the efficiency of virus transcription and assembly. This manuscript reports the analysis of HCoV-NL63 N protein by comparing the amino ...
Antimicrobial-resistant Klebsiella species isolated from free-range chicken samples in an informal settlement
(Termedia Publishing House, 2012)
Sub-therapeutic doses of antimicrobial agents are administered
routinely to poultry to aid growth and to prevent disease, with prolonged exposure
often resulting in bacterial resistance. Crossover of antibiotic resistant ...
Additive antibacterial activity of naringenin and antibiotic combinations against multidrug resistant Staphylococcus aureus
(Academic Journals, 2015)
Methicillin-resistant Staphylococcus aureus has been causing numerous problems in the health care
sector. This is mainly due to its ability to develop resistance to a number of antibiotics used to treat
staphylococcal ...
Understanding human coronavirus HCoV-NL63
(Bentham Science, 2010)
Even though coronavirus infection of humans is not normally associated with severe diseases, the identification
of the coronavirus responsible for the outbreak of severe acute respiratory syndrome showed that highly ...
Expression, purification and preliminary crystallographic analysis of recombinant human DEAD-box polypeptide 5
(International Union of Crystallography, 2010)
The DEAD-box RNA helicase DDX5 is involved in many aspects of RNA
processing and has been implicated in a number of cellular processes involving
alteration of RNA secondary structure. The N-terminal region of DDX5, ...
Human coronavirus NL63 open reading frame 3 encodes a virion-incorporated N-glycosylated membrane protein
(BioMed Central, 2010)
Background: Human pathogenic coronavirus NL63 (hCoV-NL63) is a group 1 (alpha) coronavirus commonly
associated with respiratory tract infections. In addition to known non-structural and structural proteins all
coronaviruses ...
The role of Severe Acute Respiratory Syndrome (SARS)-Coronavirus Accessory Proteins in Virus Pathogenesis
(MDPI, 2012)
A respiratory disease caused by a novel coronavirus, termed the severe acute respiratory syndrome coronavirus (SARS-CoV), was first reported in China in late 2002. The subsequent efficient human-to-human transmission of ...