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Pulmonary effects and disposition of luteolin and Artemisia afra extracts in isolated perfused lungs
(Elsevier, 2013)
ETHNOPHARMACOLOGICAL RELEVANCE: Artemisia afra (Asteraceae) is a traditional medicinal plant frequently used in steam inhalation form to treat respiratory conditions.
AIM OF THE STUDY: Quantify luteolin content in Artemisia ...
Effects of Leonotis leonurus aqueous extract on the isolated perfused rat heart
(Open Access Science Research Publisher, 2012)
The use the aqueous decoction of Leonotis leonurus (L. leonurus) (Ll) R. Br. (Lamiaceae) in the treatment of hypertension (HPT) in traditional medicine is well documented. The effect of the aqueous extract of LI on the ...
Do HIV infection and antiretroviral therapy influence multidrug-resistant tuberculosis treatment outcomes?
(Academic Journals, 2015)
The aim of this study was to find out whether human immunodeficiency virus (HIV)-infection and antiretroviral drugs influence multidrug-resistant (MDR)-tuberculosis (TB) treatment outcomes. The study compares MDR-TB treatment ...
Involvement of gamma aminobutyric acid in the anticonvulsant effect of the leaf methanol extract of Ruta graveolens L. (Rutaceae) in mice
(Asian Network for Scientific Information, 2013)
The possible involvement of gamma aminobutyric acid (GABA), in the anticonvulsant effect of Ruta graveolens L. was investigated by studying the effect of the leaf methanol extract against seizures elicited by either ...
Evaluation of the antidiarrhoeal and antidiabetic activities of the leaf aqueous extract of Syzygium cordatum hoscht. ex C.Krauss (Mytraceae) in rodents
(Asian Network for Scientific Information, 2013)
Syzygium cordatum Hoscht. ex C.Krauss is widely used by traditional medicine practitioners to treat many ailments including diarrhoea and diabetes. Despite the folklore use, little evidence can be found in literature to ...
Service learning in pharmacy: Opportunities for student learning and service delivery
(Academic Journals, 2011)
High patient load and understaffing in public health care facilities preclude the provision of optimal
pharmaceutical services in South Africa. A Service Learning in Pharmacy (SLIP) programme for the
University of the ...
The contributions of muscarinic receptors and changes in plasma aldosterone levels to the anti-hypertensive effect of Tulbaghia violacea
(BioMed Central, 2013)
Background: Tulbaghia violacea Harv. (Alliaceae) is used to treat various ailments, including hypertension (HTN) in
South Africa. This study aims to evaluate the contributions of muscarinic receptors and changes in ...
3D-QSAR and docking studies of pentacycloundecylamines at the sigma-1 (σ1) receptor
(Elsevier, 2013)
Pentacycloundecylamine (PCU) derived compounds have been shown to be promising lead structures for the development of novel drug candidates aimed at a variety of neurodegenerative and psychiatric diseases. Here we show for ...
Microwave-assisted methods for the synthesis of pentacyclo[5.4.0.02,6.03,10.05,9]undecylamines
(Elsevier, 2013)
Efficient methodologies for the preparation of pentacyclo[5..4.0.02,6.03,10.05,9]undecane (PCU) amine derivatives are described via microwave-assisted synthesis. The obtained results revealed that microwave-assisted synthetic ...
Direct inhibition of cyclooxygenase-2 enzyme by an extract of Harpagophytum procumbens, harpagoside and harpagide
(Academic Journals, 2011)
A methanolic extract of Harpagophytum procumbens as well as harpagoside and harpagide were tested
as direct inhibitors of cyclooxygenase-2 enzyme (COX-2). The H. procumbens extract demonstrated
direct inhibition (68%) of ...