Browsing Research Articles (Biotechnology) by Author "Mabhida, Sihle E."
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The association of mthfr (rs1801133) with hypertension in an indigenous South African population
Mabhida, Sihle E.; Sharma, Jyoti R.; Apalata, Teke (Frontiers Media, 2022)The current study sought to investigate the association between the methylenetetrahydrofolate reductase (MTHFR) variant (rs1801133) and the risk of developing hypertension (HTN) in an indigenous South African population.A ... -
Hypertension in African populations: Review and computational insights
Mabhida, Sihle E.; Mashatola, Lebohang; Kaur, Mandeep (MPDI, 2021)Hypertension (HTN) is a persistent public health problem affecting approximately 1.3 billion individuals globally. Treatment-resistant hypertension (TRH) is defined as high blood pressure (BP) in a hypertensive patient ... -
An in vitro study on the combination effect of metformin and n-acetyl cysteine against hyperglycaemia-induced cardiac damage
Mabhida, Sihle E. (MDPI - Publisher of Open Access Journals, 2019)Chronic hyperglycaemia is a major risk factor for diabetes-induced cardiovascular dysfunction. In a hyperglycaemic state, excess production of reactive oxygen species (ROS), coupled with decreased levels of glutathione, ...