Browsing Research Articles (Medical Bioscience) by Title
Now showing items 139-158 of 270
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In vitro comparison of the anti-proliferative effects of galenia africana on human skin cell lines
(MDPI, 2021)Malignant melanoma is the major cause of skin cancer-related deaths. Surgery in combina-tion with radiotherapy, immunotherapy or chemotherapy is used to eradicate cancer cells, however, this treatment option is limited by ... -
In vitro effects of aqueous extract of unfermented rooibos on human spermatozoa
(Wiley, 2022)The inability to conceive is a baleful experience for thousands of couples worldwide. Among different well-known reproductive techniques, medicinal plants have been utilized to treat male infertility. Medicinal plants, ... -
The in vitro effects of artificial and natural sweeteners on the immune system using whole blood culture assays
(Taylor & Francis, 2013)This article investigates the effects of commercially available artificial (aspartame, saccharin, sucralose) and natural sweeteners (brown sugar, white sugar, molasses) on the immune system. Human whole blood cultures ... -
In vitro neuroprotective effects of boophone disticha, brunsvigia bosmaniae and strumaria truncata extracts in SH-SY5Y cells
(Elsevier B.V., 2024)Parkinson's disease (PD) is the second most common neurodegenerative disorder after Alzheimer's disease. The pathological hallmarks of PD are defined by the loss of dopaminergic neurons in the substantia nigra pars compacta ... -
In vivo effects of eurycoma longifolia Jack (Tongkat Ali) extract on reproductive functions in the rat
(Blackwell, 2013)An aqueous extract of Eurycoma longifolia (Tongkat Ali; TA) roots is traditionally used to enhance male sexuality. Because previous studies are limited to only few sperm parameters or testosterone concentration, this study ... -
An in-depth bibliometric analysis and current perspective on male infertility research
(Korean Society for Sexual Medicine and Andrology, 2019)PURPOSE: Male infertility is emerging as a major, escalating global health problem that imposes the need to investigate research trends in male infertility. The purpose of this study is to analyze male infertility research ... -
An in-vitro analysis of the antimicrobial efficacy of herbal toothpastes on selected primary plaque colonizers
(iMD Publishers, 2011)Plaque associated oral disease affects a considerable portion of the population and is considered one of the major causes of tooth loss. In most cases toothbrushing only removes a limited amount of dental plaque and other ... -
An insight into the mechanism of holamine- and funtumine-induced cell death in cancer cells
(MDPI, 2020)Holamine and funtumine, steroidal alkaloids with strong and diverse pharmacological activities are commonly found in the Apocynaceae family of Holarrhena. The selective anti-proliferative and cell cycle arrest effects of ... -
Insights into the Prevalence and Resistance Patterns of Candida Species among Diabetic Patients in Cameroon: Potential Paths for Alternative Treatments
(Science and Education Publishing, 2024-05-06)The study aimed to fill the knowledge gap regarding the prevalence of Candida infections in diabetic patients and their sensitivity to antifungal drugs. Clinical samples from diabetic patients were collected at Yaoundé ... -
Interpretation of semen analysis using WHO 1999 and WHO 2010 reference values: abnormal becoming normal
(Wiley, 2017)Reference values of WHO 1999 manual were used for the interpretation of semen analysis until 2010 when new reference values were introduced which have lower cut-off compared to WHO 1999. Therefore, several men who previously ... -
Interventions to reduce pesticide exposure from the agricultural sector in Africa: A workshop report
(MDPI, 2022)Despite the fact that several cases of unsafe pesticide use among farmers in different parts of Africa have been documented, there is limited evidence regarding which specific interventions are effective in reducing ... -
The IPDGC/GP2 Hackathon - an open science event for training in data science, genomics, and collaboration using Parkinson’s disease data
(Nature Research, 2023)Open science and collaboration are necessary to facilitate the advancement of Parkinson’s disease (PD) research. Hackathons are collaborative events that bring together people with different skill sets and backgrounds to ... -
Is human Immunodeficiency Virus (HIV) stage an independent risk factor for altering the periodontal status of HIV-positive patients? A South African study
(BioMed Central, 2013)Background: The immunosuppresion in HIV patients makes them highly susceptible to microbial infections. The aim of the study was to establish whether HIV stage (as depicted by CD4+ T lymphocyte counts) could independently ... -
Is human immunodeficiency virus (HIV) stage an independent risk factor for altering the periodontal status of HIV-positive patients? A South African study
(BMC, 2013)The immunosuppresion in HIV patients makes them highly susceptible to microbial infections. The aim of the study was to establish whether HIV stage (as depicted by CD4+ T lymphocyte counts) could independently be associated ... -
Is there a link between the pathogenic human Coronavirus envelope protein and immunopathology? A review of the literature
(Frontiers Media S.A., 2020)Since the severe acute respiratory syndrome (SARS) outbreak in 2003, human coronaviruses (hCoVs) have been identified as causative agents of severe acute respiratory tract infections. Two more hCoV outbreaks have since ... -
Is there plagiarism in the most influential publications in the field of andrology?
(Wiley, 2019)Plagiarism is a common form of academic misconduct that extensively jeopardises the quality of scientific publication. The purpose of this study is to determine the extent of plagiarism in the most influential andrology ... -
Is there plagiarism in the most influential publications in the field of andrology?
(Wiley Online Library, 2019)Plagiarism is a common form of academic misconduct that extensively jeopardises the quality of scientific publication. The purpose of this study is to determine the extent of plagiarism in the most influential andrology ... -
The Ism between endothelial cilia and endothelial nanotubules is an evolving concept in the genesis of the BBB
(MDPI, 2022)The blood–brain barrier (BBB) is fundamental in maintaining central nervous system (CNS) homeostasis by regulating the chemical environment of the underlying brain parenchyma. Brain endothelial cells (BECs) constitute ... -
K21 compound, a potent antifungal agent: Implications for the treatment of fluconazole-resistant HIV-associated Candida species
(Frontiers, 2019-05-24)Background/objectives: With mucocutaneous candidiasis being highly prevalent in HIV patients, the emergence of fluconazole-resistant Candida species forms a major challenge in treating and eradicating these infections. The ... -
Leptin deficiency, caused by malnutrition, makes you susceptible to sars-cov-2 infection but could offer protection from severe Covid-19
(American Society for Microbiology, 2021)In much of the developing world, severe malnutrition is the most prevalent cause of immunodeficiency and affects up to 50% of the population in some impoverished communities. As yet, we do not know how severe acute ...