Browsing Research Articles (Medical Bioscience) by Title
Now showing items 74-93 of 270
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Effect of Cissampelos capensis rhizome extract on human spermatozoa in vitro
(Wiley, 2014)Cissampelos capensis is commonly known by the Afrikaans name ‘dawidjies’ or ‘dawidjieswortel’. C. capensis is the most important and best-known medicinal plant of the family Menispermaceae used by the Khoisan and other ... -
Effect of maternal cigarette smoking and alcohol consumption during pregnancy on birth weight and cardiometabolic risk factors in infants, children and adolescents: A systematic review protocol
(BMC, 2022)Tobacco smoking and alcohol consumption during pregnancy are particularly prevalent in low socioeconomic status populations, with an adverse association with birth outcomes and cardiometabolic risk factors. However, ... -
The effect of Nigella sativa oil and metformin on male seminal parameters and testosterone in Wistar rats exposed to an obesogenic diet
(Elsevier, 2021)Obesity is a significant global health and socio-economic challenge, and considered an important risk factor for poor health outcomes including male reproductive dysfunction and infertility. As excess adiposity causes ... -
The effect of Nigella sativa oil and metformin on male seminal parameters and testosterone in Wistar rats exposed to an obesogenic diet
(Elsevier, 2020)Obesity is a significant global health and socio-economic challenge, and considered an important risk factor for poor health outcomes including male reproductive dysfunction and infertility. As excess adiposity causes ... -
The effect of sperm DNA fragmentation on intracytoplasmic sperm injection outcome
(Wiley, 2021)Our study objective was to assess the effect of various sperm DNA fragmentation levels on clinical intracytoplasmic sperm injection outcome. This retrospective study included 392 patients who underwent ICSI and performed ... -
The effectiveness of sewage treatment processes to remove faecal pathogens and antibiotic residues
(TAYLOR & FRANCIS INC, 2013)Pathogens and antibiotics enter the aquatic environment via sewage effluents and may pose a health risk to wild life and humans.The aim of this study was to determine the levels of faecal bacteria, and selected antibiotic ... -
The effects of carbon dots on immune system biomarkers, using the Murine Macrophage cell line RAW 264.7 and human whole blood cell cultures
(MDPI, 2018)Abstract: Carbon dots (CDs) are engineered nanoparticles that are used in a number of bioapplications such as bioimaging, drug delivery and theranostics. The effects of CDs on the immune system have not been evaluated. ... -
The effects of endocrine disrupting chemicals on biomarkers of inflammation produced by lipopolysaccharide stimulated raw264.7 macrophages
(MDPI, 2019)Endocrine disrupting chemicals (EDCs) are common pollutants in the environment and can induce disruption of the endocrine and immune systems. The present study evaluated the effects of selected common environmental EDCs ... -
Effects of GnRH vaccination in wild and captive African Elephant bulls (Loxodonta africana) on reproductive organs and semen quality
(Public Library of Science, 2017)OBJECTIVES: Although the African elephant (Loxodonta africana) is classified as endangered by the International Union for Conservation of Nature (IUCN), in some isolated habitats in southern Africa, contraception is of ... -
Effects of graphene oxide nanoparticles on the immune system biomarkers produced by RAW264.7 and human whole blood cell cultures
(MDPI, 2018)Graphene oxide nanoparticles (GONPs) have attracted a lot of attention due to their many applications. These applications include batteries, super capacitors, drug delivery and biosensing. However, few studies have ... -
The effects of in utero exposure to teratogens on organ size: A prospective paediatric study
(Cambridge University Press, 2021)In low-income countries, prospective data on combined effects of in utero teratogen exposure are lacking and necessitates new research. The aim of the present study was to explore the effect of in utero teratogen exposure ... -
The effects of silver nanoparticles on RAW 264.7. Macrophages and human whole blood cell cultures
(University of the Western Cape, 2019)Silver nanoparticles (AgNPs) are commonly found in consumer products due to their antimicrobial properties. This study evaluated the effects of AgNPs on the murine macrophage cell line RAW 264.7 and human whole blood cell ... -
Effects of temperature and storage time on the motility, viability, DNA integrity and apoptosis of processed human spermatozoa
(Wiley, 2019)The aim of this study was to evaluate motility, viability, DNA integrity and apoptosis of spermatozoa when washed semen samples were kept for up to 12 days at 4–6°C and 25°C. In this experimental study, 26 normozoospermic ... -
Endocrine contribution to the sexual dysfunction in patients with advanced chronic kidney disease and the role of hyperprolactinemia
(John Wiley and Sons Inc, 2021)In this study, we investigated the prevalence of sexual dysfunction among males with advanced chronic kidney disease and the effect of treating hyperprolactinemia among these patients. In this prospective study, patients ... -
Environmental contaminants and male infertility: Effects and mechanisms
(Blackwell Publishing Ltd, 2021)The escalating prevalence of male infertility and decreasing trend in sperm quality have been correlated with rapid industrialisation and the associated discharge of an excess of synthetic substances into the environment. ... -
Enzymatic detoxification of the fumonisin mycotoxins during dry milling of maize
(Elsevier, 2021)Fumonisin esterase FumD (EC 3.1.1.87), FUMzyme® (BIOMIN, Austria), effectively detoxifies fumonisin B mycotoxins (FB) by hydrolysis and removal of the tricarballylic acid groups. The current study evaluated FumD detoxification ... -
Epididymal contribution to male infertility: An overlooked problem
(Blackwell Publishing Ltd, 2021)The diagnosis and treatment of male infertility, excluding assisted conception, are limited because of, but not limited to, poor understanding of sperm post-testicular development and storage. Many may think that sperm ... -
Ethnopharmacology, therapeutic properties and nutritional potentials of Carpobrotus edulis: A comprehensive review
(MPDI, 2020)Carpobrotus edulis, formerly known as Mesembryanthemum edule L, belongs to the Aizoaceae family of plants. It is a facultative halophytic invasive medicinal and edible succulent plant that is native to South Africa and ... -
Etiologies of sperm DNA damage and its impact on male infertility
(Blackwell Publishing Ltd, 2021)Male factor is responsible for up to 50% of infertility cases in the world. Semen analysis is considered the cornerstone of laboratory evaluation of male infertility, but it has its own drawbacks and fails to predict the ... -
Evaluation of reference values of standard semen parameters in fertile Egyptian men
(Wiley, 2018)The reference values of human semen, published in the WHO’s latest edition in 2010, were lower than those previously reported. The objective of this study was to evaluate reference values of standard semen parameters in ...