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Amino acids 1055 to 1192 in the S2 Region of severe acute respiratory syndrome Coronavirus S Protein induce neutralizing antibodies: Implications for the development of vaccines and antiviral agents
(American Society for Microbiology, 2005)
The spike (S) protein of the severe acute respiratory syndrome coronavirus (SARS-CoV) interacts with
cellular receptors to mediate membrane fusion, allowing viral entry into host cells; hence it is recognized as the
primary ...
Monoclonal Antibodies targeting the HR2 Domain and the region immediately upstream of the HR2 of the S Protein neutralize in Vitro Infection of Severe Acute Respiratory Syndrome Coronavirus
(American Society for Microbiology, 2006)
We have previously shown that an Escherichia coli-expressed, denatured spike (S) protein fragment of the
severe acute respiratory coronavirus, containing residues 1029 to 1192 which include the heptad repeat 2
(HR2) ...