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Trends in Genotypic HIV-1 Antiretroviral resistance between 2006 and 2012 in South African Patients receiving first- and second line antiretroviral treatment regimensTrends in Genotypic HIV-1 Antiretroviral resistance between 2006 and 2012 in South African Patients receiving first- and second line antiretroviral treatment regimens
(University of the Western CapePublic Library of Science -- PLoS, 2013)
South Africa's national antiretroviral (ARV) treatment program expanded in 2010 to include the nucleoside
reverse transcriptase (RT) inhibitors (NRTI) tenofovir (TDF) for adults and abacavir (ABC) for children. We ...
RAMICS: Trainable, high-speed and biologically relevant alignment of high-throughput sequencing reads to coding DNA
(Oxford University Press, 2014)
The challenge presented by high-throughput sequencing necessitates the development of novel
tools for accurate alignment of reads to reference sequences. Current approaches focus on using heuristics to map reads quickly ...