Browsing Faculty of Natural Sciences by Subject "11β-hydroxysteroid dehydrogenase"

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Crystal structure, hirshfeld surface analysis and dft studies of 5-(adamantan-1-yl)-3-[(4-chlorobenzyl)sulfanyl]-4-methyl-4h-1,2,4-triazole, a potential 11β-hsd1 inhibitor

Joubert, Jacques (Scientific Reports, 2019)

5-(Adamantan-1-yl)-3-[(4-chlorobenzyl)sulfanyl]-4-methyl-4H-1,2,4-triazole (4) was identified as a potential 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor and this paper describes the in-depth structural ...