Search
Now showing items 1-2 of 2
Potential broad spectrum inhibitors of the coronavirus 3CLpro: A virtual screening and structure-based drug design study
(MDPI, 2015)
Human coronaviruses represent a significant disease burden; however, there is currently no antiviral strategy to combat infection. The outbreak of severe acute respiratory syndrome (SARS) in 2003 and Middle East respiratory ...
The flexible, extended coil of the pdz-binding motif of the three deadly human coronavirus e proteins plays a role in pathogenicity
(MDPI, 2022)
The less virulent human (h) coronaviruses (CoVs) 229E, NL63, OC43, and HKU1 cause
mild, self-limiting respiratory tract infections, while the more virulent SARS-CoV-1, MERS-CoV, and
SARS-CoV-2 have caused severe outbreaks. ...