Search
Now showing items 1-10 of 18
The role of infections and leukocytes in male infertility
(Blackwell Publishing Ltd, 2021)
Declining birth rates are one of the problems facing society today. Male counterparts are responsible for about half of the infertility cases, and genitourinary tract infections may play a contributing role in approximately ...
Environmental contaminants and male infertility: Effects and mechanisms
(Blackwell Publishing Ltd, 2021)
The escalating prevalence of male infertility and decreasing trend in sperm quality have been correlated with rapid industrialisation and the associated discharge of an excess of synthetic substances into the environment. ...
Diagnostic value of advanced semen analysis in evaluation of male infertility
(Blackwell Publishing Ltd, 2021)
Conventional semen analysis is the standard of care to initially evaluate the fertility status of a male patient. However, it has some limitations and among these are failure to correctly identify the aetiology underlying ...
An update on the techniques used to measure oxidative stress in seminal plasma
(Blackwell Publishing Ltd, 2021)
Reactive oxygen species (ROS) are produced in significant amounts by spermatozoa and leucocytes. They are necessary to carry out various physiological functions such as sperm capacitation, hyperactivation, acrosome reaction, ...
Protein profiling in unlocking the basis of varicocele-associated infertility
(Blackwell Publishing Ltd, 2021)
Varicocele is one of the major causes of male infertility and has a negative impact on spermatogenesis. The conventional semen analysis does not reveal the underlying subcellular mechanisms associated with defects in ...
Male infertility
(Lancet Publishing Group, 2021)
It is estimated that infertility affects 8–12% of couples globally, with a male factor being a primary or contributing cause in approximately 50% of couples. Causes of male subfertility vary highly, but can be related to ...
Comparative analysis of tests used to assess sperm chromatin integrity and DNA fragmentation
(Blackwell Publishing Ltd, 2021)
Male infertility has a complex etiology, and many times, the cause is unknown. While routine semen analysis provides an overview of basic semen parameters, such as sperm concentration, motility, viability and morphology, ...
TUNEL assay—Standardized method for testing sperm DNA fragmentation
(Blackwell Publishing Ltd, 2021)
Sperm DNA integrity is important for normal functions such as fertilization, implantation, pregnancy and fetal development. Sperm DNA fragmentation (SDF) is more common in infertile men and may be responsible for poor ...
Association of XRCC1 and ERCC2 promoters’ methylation with chromatin condensation and sperm DNA fragmentation in idiopathic oligoasthenoteratozoospermic men
(Blackwell Publishing Ltd, 2021)
The aim of the study was to investigate whether the promoter methylation of XRCC1 and ERCC2 genes is associated with sperm DNA fragmentation and chromatin condensation in idiopathic oligoasthenoteratozoospermic men. This ...
Evaluation of seminal oxidation–reduction potential in male infertility
(Blackwell Publishing Ltd, 2021)
The role of oxidative stress in male infertility has been broadly recognised, and the search for a new marker to determine the redox environment in semen has gained considerable interest. Oxidation–reduction potential (ORP) ...