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Genetic polymorphisms and haplotypes of the organic cation transporter 1 gene (SLC22A1) in the Xhosa population of South Africa
(Brazilian Society of Genetics, 2014)
Human organic cation transporter 1 is primarily expressed in hepatocytes and mediates the electrogenic transport of
various endogenous and exogenous compounds, including clinically important drugs. Genetic polymorphisms ...
RAMICS: Trainable, high-speed and biologically relevant alignment of high-throughput sequencing reads to coding DNA
(Oxford University Press, 2014)
The challenge presented by high-throughput sequencing necessitates the development of novel
tools for accurate alignment of reads to reference sequences. Current approaches focus on using heuristics to map reads quickly ...