Browsing Research Publications by Author "Krane, Jeffrey F."
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Diffuse staining for activated NOTCH1 correlates with NOTCH1 mutation status and is associated with worse outcome in adenoid cystic carcinoma
Sajed, Dipti P.; Faquin, William C.; Carey, Chris; Severson, Eric A.; Afrogheh, Amir H.; Johnson, Carl A.; Blacklow, Stephen C.; Chau, Nicole G.; Lin, Derrick T.; Krane, Jeffrey F.; Jo, Vickie Y.; Garcia, Joaquín J.; Sholl, Lynette M.; Aster, Jon C. (Lippincott, Williams & Wilkins, 2017)NOTCH1 is frequently mutated in adenoid cystic carcinoma (ACC). To test the idea that immunohistochemical (IHC) staining can identify ACCs with NOTCH1 mutations, we performed IHC for activated NOTCH1 (NICD1) in 197 cases ...