Human African trypanosomiasis research gets booost: unravelling the tsetse Genome

Abstract

Human African trypanosomiasis (HAT), also known as sleeping sickness, is a neglected disease that impacts 70 million people distributed over 1.55 million km2 in sub-Saharan Africa. Trypanosoma brucei gambiense accounts for almost 90% of the infections in central and western Africa, the remaining infections being from T. b. rhodesiense in eastern Africa. Furthermore, the animal diseases caused by related parasites inflict major economic losses to countries already strained. The parasites are transmitted to the mammalian hosts through the bite of an infected tsetse fly.